Protein Alignment PTPA and RRD1

DIOPT Version :10

• Sequence 1: XP_054219193.1
• Gene: PTPA / 5524
• HGNCID: 9308
• Length: 524
• Species: Homo sapiens
• Sequence 2: NP_012113.1
• Gene: RRD1 / 854653
• SGDID: S000001415
• Length: 393
• Species: Saccharomyces cerevisiae
• Alignment Length: 286
• Identity: 120/286 - (41%)
• Similarity: 162/286 - (56%)
• Gaps: 19/286 - (6%)

Human   127 VHEEKEQAAKQSVSCDECI-PLPRAGHCAPSEA-IEKLVALLNTLDRWIDETPPVDQPSRFGNKA 189
            :|..|....|.:.....|. |.|.|  .|.|.| :..|:.:|:.|...||||||:..|.|:||.|
Yeast    35 IHRIKYHLHKYTTLISHCSDPDPHA--TASSIAMVNGLMGVLDKLAHLIDETPPLPGPRRYGNLA 97

Human   190 YRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKI 254
            .|.|:.||||.....:..::|:.....|||:..||..|.|:|||:|||||||.:|.|.:..|..:
Yeast    98 CREWHHKLDERLPQWLQEMLPSEYHEVVPELQYYLGNSFGSSTRLDYGTGHELSFMATVAALDML 162

Human   255 GV---LRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSS--QLID 314
            |:   :|..|    ||.:||:|..:||:|..||.:|||||.|||||||...|.:|.|||  ||:|
Yeast   163 GMFPHMRGAD----VFLLFNKYYTIMRRLILTYTLEPAGSHGVWGLDDHFHLVYILGSSQWQLLD 223

Human   315 -HPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNIS-AVPSWSKVNQGLI 377
             ...|:||..:|:..|.|......:.:.|.||.|:|.|||.|||..|::|: .||.||||.:||:
Yeast   224 AQAPLQPREILDKSLVREYKDTNFYCQGINFINEVKMGPFEEHSPILYDIAVTVPRWSKVCKGLL 288

Human   378 RMYKAEVSGGWPVCPSLLPHLVLGWG 403
            :||..||...:||    :.|...|.|
Yeast   289 KMYSVEVLKKFPV----VQHFWFGTG 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPA	XP_054219193.1	PTPA	76..390	CDD:460802	115/271 (42%)
RRD1	NP_012113.1	LAG1	1..387	CDD:227390	120/286 (42%)