Protein Alignment PTPA and Ptpa

DIOPT Version :9

• Sequence 1: XP_011517136.1
• Gene: PTPA / 5524
• HGNCID: 9308
• Length: 463
• Species: Homo sapiens
• Sequence 2: NP_523466.2
• Gene: Ptpa / 33555
• FlyBaseID: FBgn0016698
• Length: 398
• Species: Drosophila melanogaster
• Alignment Length: 391
• Identity: 158/391 - (40%)
• Similarity: 223/391 - (57%)
• Gaps: 30/391 - (7%)

Human    78 KEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETP 142
            |::..:.|||.|::|:|:.|.||:|...:..::|.|.|.|...||.::||:.|.:.|::.:::.|
  Fly    17 KKVQNLGDMGVWQKSRAFHDLIGYINGTSSAIQGIKTTDEIFESEMLKKLLRLFDALEKLVEQNP 81

Human   143 PVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEA 207
            |::||.||||||||.|...:.|....|:..::|........|:..||.||.||:||||||||||.
  Fly    82 PLEQPQRFGNKAYRDWAQAMRELLPELLEQLLPDDKKRYQVELGQYLTESFGNATRIDYGTGHEL 146

Human   208 AFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIW 272
            :|..|||.|.|..:|:..|.::...::||||||:.|:||:||.||||||||||.||||||:||||
  Fly   147 SFLFFLCSLFKAEILQERDIVSAALRLFNRYLELARQLQRTYNMEPAGSQGVWSLDDFQFVPFIW 211

Human   273 GSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKV 337
            ||:||......:|..||||..:.|....:||:.||.:|.::|||.|.|||||||:|:.||:|:|:
  Fly   212 GSAQLAVKSPFDPSKFVDEAIITEYKDHFMFISCIDYICKVKTGHFGEHSNQLWSITDVPTWAKI 276

Human   338 NQGLIRMYKAEVSGGWPVCPSLLPHLVLG---WGQSKRCGTWGSCFLLPH---------CFAL-N 389
            |.||::||:.|:...:||    :.|:..|   ..:....||..|...|.|         |... |
  Fly   277 NAGLVKMYQKEILSKFPV----IQHVYFGELMTFEPVSSGTTLSNARLGHVAPPPSKRICIGTPN 337

Human   390 LRPAPLTLGASESPIWGMGSQRSTSHPSPEKLQSSSVL------MSLEAEARTCCMGSGGDGGLP 448
            |.|......|...|...:..:::....|.|...:|.||      .||.|.|.       |.|..|
  Fly   338 LVPPVPVATAPPPPAESLSIEQNVGDSSSESSDNSVVLRPSTSSSSLVAAAE-------GSGDKP 395

Human   449 S 449
            |
  Fly   396 S 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPA	XP_011517136.1	PTPA	76..355	CDD:281137	130/276 (47%)
Ptpa	NP_523466.2	PTPA	17..308	CDD:281137	134/294 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158285
Domainoid	1	1.000	286	1.000	Domainoid score	I1616
eggNOG	1	0.900	-	-		E1_COG5057
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6149
Inparanoid	1	1.050	294	1.000	Inparanoid score	I2776
Isobase	1	0.950	-	0	Normalized mean entropy	S1048
OMA	1	1.010	-	-		QHG54183
OrthoDB	1	1.010	-	-		D1165705at2759
OrthoFinder	1	1.000	-	-		FOG0002736
OrthoInspector	1	1.000	-	-		oto89255
orthoMCL	1	0.900	-	-		OOG6_101438
Panther	1	1.100	-	-	LDO	PTHR10012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1030
SonicParanoid	1	1.000	-	-		X2111
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750