Protein Alignment LRRC1 and Lrrc1

DIOPT Version :10

• Sequence 1: NP_060684.4
• Gene: LRRC1 / 55227
• HGNCID: 14307
• Length: 524
• Species: Homo sapiens
• Sequence 2: NP_001014290.1
• Gene: Lrrc1 / 367113
• RGDID: 1549773
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 484/524 - (92%)
• Similarity: 514/524 - (98%)
• Gaps: 0/524 - (0%)

Human     1 MFHCIPLWRCNRHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLG 65
            |||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MFHCIPLWRCNRHVEAIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLG 65

Human    66 LSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNL 130
            |||||:|||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||
  Rat    66 LSDNEVQRLPPEIANFMQLVELDVSRNDIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNL 130

Human   131 TCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGA 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||
  Rat   131 TCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYSLPESIGA 195

Human   196 LLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPD 260
            ||||||||||||||||||||||||:||||||||||||||||||||||.||||||:|||||||:||
  Rat   196 LLHLKDLWLDGNQLSELPQEIGNLRNLLCLDVSENRLERLPEEISGLISLTDLVVSQNLLETVPD 260

Human   261 GIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLV 325
            ||||||||||||:|||||||||||:|:||:|||||||||:|||||.||||||||:||||||||||
  Rat   261 GIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPTSIGKLKKLNNLNADRNKLV 325

Human   326 SLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPLSLTALKLKALWLSDN 390
            ||||||||||||||||:|||||||||:|||||.||||||||||||.|||||||.|||||||||||
  Rat   326 SLPKEIGGCCSLTVFCIRDNRLTRIPSEVSQAMELHVLDVAGNRLHHLPLSLTTLKLKALWLSDN 390

Human   391 QSQPLLTFQTDTDYTTGEKILTCVLLPQLPSEPTCQENLPRCGALENLVNDVSDEAWNERAVNRV 455
            |||||||||||.|:||||||||||||||:||||.|||:||||||:|:||||||:|||::.:|:||
  Rat   391 QSQPLLTFQTDVDHTTGEKILTCVLLPQMPSEPICQESLPRCGAMESLVNDVSEEAWDDHSVHRV 455

Human   456 SAIRFVEDEKDEEDNETRTLLRRATPHPGELKHMKKTVENLRNDMNAAKGLDSNKNEVNHAIDRV 520
            |||||:|||||||:|:||||.|||||||||||:||||||||||||||||||||||||||||.:||
  Rat   456 SAIRFLEDEKDEEENQTRTLQRRATPHPGELKNMKKTVENLRNDMNAAKGLDSNKNEVNHATERV 520

Human   521 TTSV 524
            ||||
  Rat   521 TTSV 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LRRC1	NP_060684.4	LRR 1	11..34		21/22 (95%)
		PRK15370	<23..>125	CDD:185268	99/101 (98%)
		LRR 2	35..58		22/22 (100%)
		leucine-rich repeat	38..60	CDD:275380	21/21 (100%)
		LRR 3	60..81		19/20 (95%)
		leucine-rich repeat	61..83	CDD:275380	20/21 (95%)
		LRR 4	83..105		20/21 (95%)
		leucine-rich repeat	84..106	CDD:275380	20/21 (95%)
		leucine-rich repeat	107..129	CDD:275380	21/21 (100%)
		LRR 5	107..126		18/18 (100%)
		LRR 6	127..149		21/21 (100%)
		leucine-rich repeat	130..152	CDD:275380	21/21 (100%)
		LRR	133..424	CDD:443914	270/290 (93%)
		LRR 7	150..172		21/21 (100%)
		leucine-rich repeat	153..175	CDD:275380	21/21 (100%)
		LRR 8	173..196		21/22 (95%)
		leucine-rich repeat	176..198	CDD:275380	20/21 (95%)
		LRR 9	198..218		19/19 (100%)
		leucine-rich repeat	199..221	CDD:275380	21/21 (100%)
		LRR 10	219..242		21/22 (95%)
		leucine-rich repeat	222..244	CDD:275380	21/21 (100%)
		LRR 11	244..264		17/19 (89%)
		leucine-rich repeat	245..267	CDD:275380	19/21 (90%)
		LRR 12	265..288		20/22 (91%)
		LRR 13	290..310		16/19 (84%)
		leucine-rich repeat	291..313	CDD:275380	19/21 (90%)
		LRR 14	311..334		21/22 (95%)
		leucine-rich repeat	314..336	CDD:275380	20/21 (95%)
		LRR 15	336..356		17/19 (89%)
		LRR 16	357..380		20/22 (91%)
		leucine-rich repeat	360..381	CDD:275380	18/20 (90%)
		LRR 17	382..405		21/22 (95%)
Lrrc1	NP_001014290.1	LRR	38..322	CDD:443914	269/283 (95%)
		leucine-rich repeat	38..60	CDD:275380	21/21 (100%)
		leucine-rich repeat	61..83	CDD:275380	20/21 (95%)
		leucine-rich repeat	84..106	CDD:275380	20/21 (95%)
		leucine-rich repeat	107..129	CDD:275380	21/21 (100%)
		leucine-rich repeat	130..152	CDD:275380	21/21 (100%)
		leucine-rich repeat	153..175	CDD:275380	21/21 (100%)
		leucine-rich repeat	176..198	CDD:275380	20/21 (95%)
		leucine-rich repeat	199..221	CDD:275380	21/21 (100%)
		leucine-rich repeat	222..244	CDD:275380	21/21 (100%)
		leucine-rich repeat	245..290	CDD:275380	39/44 (89%)
		PRK15370	<274..>380	CDD:185268	95/105 (90%)
		leucine-rich repeat	314..336	CDD:275380	20/21 (95%)