Protein Alignment LRRC1 and Lrrc1

DIOPT Version :10

• Sequence 1: NP_060684.4
• Gene: LRRC1 / 55227
• HGNCID: 14307
• Length: 524
• Species: Homo sapiens
• Sequence 2: XP_030100078.1
• Gene: Lrrc1 / 214345
• MGIID: 2442313
• Length: 580
• Species: Mus musculus
• Alignment Length: 432
• Identity: 397/432 - (91%)
• Similarity: 421/432 - (97%)
• Gaps: 0/432 - (0%)

Human    93 EIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLE 157
            :||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   149 DIPEIPESIAFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLE 213

Human   158 LRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   214 LRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 278

Human   223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGE 287
            ||||||||||||||||||||||||.||||||||||||:||||||||||||:|||||||||||:|:
Mouse   279 LCLDVSENRLERLPEEISGLTSLTYLVISQNLLETIPEGIGKLKKLSILKLDQNRLTQLPEAIGD 343

Human   288 CESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPA 352
            ||:|||||||||:||||||||||||||||||||||||||||||||||||||:||:|||||||:||
Mouse   344 CENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTMFCIRDNRLTRLPA 408

Human   353 EVSQATELHVLDVAGNRLLHLPLSLTALKLKALWLSDNQSQPLLTFQTDTDYTTGEKILTCVLLP 417
            |||||.||||||||||||.|||||||.||||||||||||||||||||||.|..||||||||||||
Mouse   409 EVSQAVELHVLDVAGNRLHHLPLSLTTLKLKALWLSDNQSQPLLTFQTDIDRATGEKILTCVLLP 473

Human   418 QLPSEPTCQENLPRCGALENLVNDVSDEAWNERAVNRVSAIRFVEDEKDEEDNETRTLLRRATPH 482
            |:||||.|||:||||||||:||.|:|:||||:|:|:|||||||:||||||::||||||.||||||
Mouse   474 QMPSEPICQESLPRCGALESLVTDMSEEAWNDRSVHRVSAIRFLEDEKDEDENETRTLQRRATPH 538

Human   483 PGELKHMKKTVENLRNDMNAAKGLDSNKNEVNHAIDRVTTSV 524
            |||||:||||||||||||||||||||||||||||.:||||||
Mouse   539 PGELKNMKKTVENLRNDMNAAKGLDSNKNEVNHAAERVTTSV 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LRRC1	NP_060684.4	LRR 1	11..34
		PRK15370	<23..>125	CDD:185268	29/31 (94%)
		LRR 2	35..58
		leucine-rich repeat	38..60	CDD:275380
		LRR 3	60..81
		leucine-rich repeat	61..83	CDD:275380
		LRR 4	83..105		9/11 (82%)
		leucine-rich repeat	84..106	CDD:275380	10/12 (83%)
		leucine-rich repeat	107..129	CDD:275380	21/21 (100%)
		LRR 5	107..126		18/18 (100%)
		LRR 6	127..149		21/21 (100%)
		leucine-rich repeat	130..152	CDD:275380	21/21 (100%)
		LRR	133..424	CDD:443914	273/290 (94%)
		LRR 7	150..172		21/21 (100%)
		leucine-rich repeat	153..175	CDD:275380	21/21 (100%)
		LRR 8	173..196		22/22 (100%)
		leucine-rich repeat	176..198	CDD:275380	21/21 (100%)
		LRR 9	198..218		19/19 (100%)
		leucine-rich repeat	199..221	CDD:275380	21/21 (100%)
		LRR 10	219..242		22/22 (100%)
		leucine-rich repeat	222..244	CDD:275380	21/21 (100%)
		LRR 11	244..264		17/19 (89%)
		leucine-rich repeat	245..267	CDD:275380	19/21 (90%)
		LRR 12	265..288		20/22 (91%)
		LRR 13	290..310		17/19 (89%)
		leucine-rich repeat	291..313	CDD:275380	20/21 (95%)
		LRR 14	311..334		22/22 (100%)
		leucine-rich repeat	314..336	CDD:275380	21/21 (100%)
		LRR 15	336..356		16/19 (84%)
		LRR 16	357..380		20/22 (91%)
		leucine-rich repeat	360..381	CDD:275380	18/20 (90%)
		LRR 17	382..405		21/22 (95%)
Lrrc1	XP_030100078.1	PRK12323	<4..>158	CDD:481241	7/8 (88%)
		LRR	153..>453	CDD:443914	285/299 (95%)
		leucine-rich repeat	163..185	CDD:275380	21/21 (100%)
		leucine-rich repeat	186..208	CDD:275380	21/21 (100%)
		leucine-rich repeat	209..231	CDD:275380	21/21 (100%)
		leucine-rich repeat	232..254	CDD:275380	21/21 (100%)
		leucine-rich repeat	255..277	CDD:275380	21/21 (100%)
		leucine-rich repeat	278..300	CDD:275380	21/21 (100%)
		leucine-rich repeat	301..346	CDD:275380	39/44 (89%)
		leucine-rich repeat	347..369	CDD:275380	20/21 (95%)
		leucine-rich repeat	370..392	CDD:275380	21/21 (100%)
		leucine-rich repeat	416..437	CDD:275380	18/20 (90%)