Protein Alignment TMLHE and CG10814

DIOPT Version :10

• Sequence 1: NP_060666.1
• Gene: TMLHE / 55217
• HGNCID: 18308
• Length: 421
• Species: Homo sapiens
• Sequence 2: NP_610868.1
• Gene: CG10814 / 36481
• FlyBaseID: FBgn0033830
• Length: 402
• Species: Drosophila melanogaster
• Alignment Length: 372
• Identity: 110/372 - (29%)
• Similarity: 182/372 - (48%)
• Gaps: 36/372 - (9%)

Human    69 MRFDYVWLRDHCRSASCYNSKTHQR------SLDTASVDLCIKPKTIRLDETTLFFTWPDGHVTK 127
            |:|..:||||:||...||..:|..|      .|||:   :.:..:::.:|:..|...|.|||.::
  Fly    38 MQFPDIWLRDNCRCEECYLPQTLSRLPQLWNHLDTS---VRVLRQSVDVDQRVLCIEWSDGHTSQ 99

Human   128 YDLNWLVKNSYE-GQKQKVIQ-----PRILWNAEIYQQ-AQVPSVDCQSFLETNEGLKKFLQNFL 185
            |..:||.:..:. ..:|:.::     .:.||:...::: .||  ...|..|:.:..|:::||:..
  Fly   100 YPFSWLRERDFSYANRQRYLRDFYRPEQKLWSGLDFEKIRQV--FYYQELLDCDSALQQWLQHLA 162

Human   186 LYGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTTYFQE 250
            :||:|.|:..|...:...:|:.|:..:|.|.||..:...:.....:.||....|..|||..||:.
  Fly   163 VYGVAMVKEAPLDMDVLRRLSNRVGFMRRTTYGEEFSVRAQPGGSNYAYLAAPLPLHTDMPYFEY 227

Human   251 PCGIQVFHCLKHEGT-GGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDVGECHNHMIG 314
            ..|:.:.|.|:...: ||..||.|.||.||.:.::.||:|.:|.:.|:....|...|:...|.|.
  Fly   228 LPGVTMLHTLEQSASPGGVNLLADAFYVAEVMRERYPEQFRVLCQTPVDWADIGSDGDLQFHNIW 292

Human   315 IGPVLNIYPWNKELYLIRYNNY--DRAVINTVPYDVVHRWYTAHRTLTIELRRPENEFWVKLKPG 377
            ..||:|:   :.|...:|.|:.  .|....:||.:.|..||.|..|. :.|.. |:....|..||
  Fly   293 RAPVINL---DAEGRCVRINHSIPQRDSHFSVPVEQVRPWYEAMATF-VGLAH-EHSCRFKTTPG 352

Human   378 RVLFIDNWRVLHGRECFTGY-------RQLCGCYLTRDDVLNTARLL 417
            .||..||.|::|||   |||       |.:.|.::..|.|.:..|:|
  Fly   353 DVLTFDNLRLVHGR---TGYDDTDRNVRHILGAFVDWDIVYSRLRVL 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMLHE	NP_060666.1	carnitine_TMLD	70..419	CDD:274119	109/371 (29%)
CG10814	NP_610868.1	GBBH-like_N	22..106	CDD:461840	23/70 (33%)
		CAS_like	119..387	CDD:238154	81/277 (29%)