Protein Alignment ATAD3A and bor

DIOPT Version :10

• Sequence 1: NP_060658.3
• Gene: ATAD3A / 55210
• HGNCID: 25567
• Length: 634
• Species: Homo sapiens
• Sequence 2: NP_524996.1
• Gene: bor / 53565
• FlyBaseID: FBgn0287225
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 640
• Identity: 367/640 - (57%)
• Similarity: 451/640 - (70%)
• Gaps: 60/640 - (9%)

Human     1 MSWLFGINK-GPK-------GEGAGPPPPLPPAQPGAEGGGDRGLGDRPAPKDKWSNFDPTGLER 57
            ||||.|.|: .|:       .||.|...  |..:...|..||..|........:...||.:.|||
  Fly     1 MSWLLGRNRQQPQPDQTAGFSEGGGAAD--PEGRTAGEKSGDSQLSRAERKAMEAYRFDSSALER 63

Human    58 AAKAARELEHSRYAKDALNLAQMQEQTLQLEQQSKLKMRLEALSLLHTLVWAWSLCRAGAVQTQE 122
            ||.||:.||.|::|::||.|::|||.|.|.|..:|:|
  Fly    64 AADAAKTLERSKHAREALELSKMQEATRQTEYNTKVK---------------------------- 100

Human   123 RLSGSASPEQVPAGECCALQEYEAAVEQLKSEQIRAQAEERRKTLSEETRQHQARAQYQDKLARQ 187
                                ||||.:||.|.||.|...|||||||.|||:|.|.||||||:|:|:
  Fly   101 --------------------EYEAHIEQAKVEQKRIDHEERRKTLIEETKQQQQRAQYQDQLSRK 145

Human   188 RYEDQLKQQQLLNEENLRKQEESVQKQEAMRRATVEREMELRHKNEMLRVEAEARARAKAERENA 252
            ||||||.|||.:.||||||||||||:||||||.|:|.|:|::.||.:..:|.|.||:|:.:|||.
  Fly   146 RYEDQLLQQQRVQEENLRKQEESVQRQEAMRRQTIEHEIEMKEKNRLKLLEHELRAKARVDRENR 210

Human   253 DIIREQIRLKAAEHRQTVLESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATL 317
            ||..|:|||||.|||.||||.|:||||:.|.|..|.:||||||.....||:|||:|||:||.||.
  Fly   211 DINLEKIRLKAQEHRTTVLEGIKTAGTVIGAGAEAMLTDWDKVLTAAGGLSLLALGVYTAKGATG 275

Human   318 VAGRFIEARLGKPSLVRETSRITVLEALRHPIQVSRRLLSRPQDALEGVVLSPSLEARVRDIAIA 382
            |..|::|||:|||:||.||||...|:||::|:...:||.::|.|||:||||:|.||.|:||||||
  Fly   276 VVSRYVEARIGKPTLVGETSRFAFLDALKNPLHYLKRLRAKPTDALQGVVLNPKLEERLRDIAIA 340

Human   383 TRNTKKNRSLYRNILMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWA 447
            |:||:.|:.:|||:||:||||||||:||||||.|||||:||||||||||||:|||||:||:|||:
  Fly   341 TKNTRINKGMYRNVLMHGPPGTGKTMFAKKLAEHSGMDFAIMTGGDVAPMGKEGVTAIHKVFDWS 405

Human   448 NTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLYRTGQHSNKFMLVLASNQPEQFDWAIN 512
            :||||||||||||||||||||::|||||||||.||||||||.:.:.|||||||||.|||||:|||
  Fly   406 HTSRRGLLLFVDEADAFLRKRSSEKISEDLRAALNAFLYRTSEQNPKFMLVLASNTPEQFDYAIN 470

Human   513 DRINEMVHFDLPGQEERERLVRMYFDKYVLKPATEGKQRLKLAQFDYGRKCSEVARLTEGMSGRE 577
            ||::|||.|.|||.||||||:|:|||||||:||..|.:|.||..||||:.||::|.|.|||||||
  Fly   471 DRLDEMVEFTLPGLEERERLLRLYFDKYVLQPAAAGAKRFKLDTFDYGKTCSKMAALCEGMSGRE 535

Human   578 IAQLAVSWQATAYASEDGVLTEAMMDTRVQDAVQQHQQKMCWLKAEGPGRGDEPS 632
            |::|.|||||..||||||:|||.|:..|...|.|||:|||.||..:  .|.|..|
  Fly   536 ISKLGVSWQAAVYASEDGLLTEKMVLDRCYSAAQQHKQKMAWLSDQ--ERADHKS 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATAD3A	NP_060658.3	ATAD3_N	42..334	CDD:463442	145/291 (50%)
		RecA-like_ATAD3-like	372..521	CDD:410920	118/148 (80%)
bor	NP_524996.1	ATAD3_N	35..291	CDD:463442	148/303 (49%)
		RecA-like_ATAD3-like	330..479	CDD:410920	118/148 (80%)