Protein Alignment SLC25A36 and Shawn

DIOPT Version :10

• Sequence 1: XP_047304396.1
• Gene: SLC25A36 / 55186
• HGNCID: 25554
• Length: 343
• Species: Homo sapiens
• Sequence 2: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Alignment Length: 366
• Identity: 97/366 - (26%)
• Similarity: 148/366 - (40%)
• Gaps: 71/366 - (19%)

Human    19 AAGPGRTPQSSRRRGSRAALRSL---ASDFAC-GGTVGAILTCPLEVVKTRLQSSSVTLYISEVQ 79
            ||...:.|..:.....|..:|.|   ||  || |..|.|....||:|:|||||:....|..::..
  Fly    18 AAASSQNPSKATMTDPRFRIRPLQQVAS--ACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCF 80

Human    80 L-----------------NTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSR 127
            |                 |..|.....|.  .|.:.....|...||..||:.||.|.|:...||.
  Fly    81 LYCNGLMDHICPCGPDTPNPAAAKPAPRF--SGTIDAFIKISRTEGIGSLWSGLSPTLISALPST 143

Human   128 AIYFAAYSNCKEKLNDVF-----DPDSTQ----------VHMISAAMAGFTAITATNPIWLIKTR 177
            .|||.||...|.:..|:.     .||:..          |.:::.......|:|..:|:.||:|:
  Fly   144 IIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTK 208

Human   178 LQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTA 242
            :|.......|    .|..:|:|.|:.|:.|.:|       |:..|::..|.:..|.....||..:
  Fly   209 MQSQRMTHAE----MFGTIRQVVQSQGVLGLWR-------GLPPTILRDVPFSGIYWTCYEYLKS 262

Human   243 STMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLR-EEGTKY------------R 294
            |.      .|.|.: |.....|.|.|.:.|.||..|.:||:|..: |.|.|:            :
  Fly   263 SF------GVVEPT-FSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATK 320

Human   295 SFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 335
            |....|:.:.:..|..:::.||...|.:..|..|||::::|
  Fly   321 SVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFE 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A36	XP_047304396.1	Mito_carr	40..145	CDD:395101	40/125 (32%)
		Mito_carr	146..240	CDD:395101	23/103 (22%)
		Mito_carr	258..343	CDD:395101	25/91 (27%)
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	39/123 (32%)
		Mito_carr	178..265	CDD:395101	23/103 (22%)
		Mito_carr	268..371	CDD:395101	26/95 (27%)