Protein Alignment PRMT6 and Art1

DIOPT Version :10

• Sequence 1: NP_060607.2
• Gene: PRMT6 / 55170
• HGNCID: 18241
• Length: 375
• Species: Homo sapiens
• Sequence 2: NP_650017.1
• Gene: Art1 / 41295
• FlyBaseID: FBgn0037834
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 371
• Identity: 125/371 - (33%)
• Similarity: 189/371 - (50%)
• Gaps: 46/371 - (12%)

Human     4 PKKRKLESGGG-----------------GEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECY 51
            |.:..:||..|                 .||..|......|:        ..|.|:   .|::.|
  Fly     7 PMEAAVESATGITPNSNANSNNVAKKLPAEGSTGDNPNANAD--------EMTSRD---YYFDSY 60

Human    52 SDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAI 116
            :...:||||:.|.|||..||..:..|....:||||||||.||||||:|.|:|||.:|.||:.|.|
  Fly    61 AHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAGAAQVIAVDCSNI 125

Human   117 WQQAREVVRFNGLEDRVHVLPGPVETVELP---EQVDAIVSEWMGYGLLHESMLSSVLHARTKWL 178
            .:.||:||..|.|:|.:.|:.|.:|.:|||   |.||.|:||||||.|.:||||.:||:||.|||
  Fly   126 IEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFYESMLDTVLYARDKWL 190

Human   179 KEGGLLLPASAELFIAPISD-QMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLS 242
            |:.|::.|....|:|..|.| |..:.::.:|..|   ||.||||:...|.      :|.:|..:.
  Fly   191 KKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDV---YGFDMSCIRKVAV------TEPLVDVVD 246

Human   243 GEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVL 307
            .:.|::......:::|...   |:.:.....:|......:..:.....:|.:.|.  :..|.|..
  Fly   247 PKQVVSTSCMVKEVDLYTV---QKADLNFSSKFSLCIKRNDFVQALVTYFNIEFT--KCHKRLGF 306

Human   308 STSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRL 353
            ||||....|||||.:.||::.:..:::.:::|...:.|:..|.|.|
  Fly   307 STSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDL 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRMT6	NP_060607.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		8/50 (16%)
		COG4076	51..>223	CDD:443253	87/175 (50%)
Art1	NP_650017.1	COG4076	66..>231	CDD:443253	84/167 (50%)