Sequence 1: | NP_060595.3 | Gene: | ARHGEF10L / 55160 | HGNCID: | 25540 | Length: | 1279 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_996333.4 | Gene: | PsGEF / 31224 | FlyBaseID: | FBgn0264598 | Length: | 2777 | Species: | Drosophila melanogaster |
Alignment Length: | 1521 | Identity: | 264/1521 - (17%) |
---|---|---|---|
Similarity: | 444/1521 - (29%) | Gaps: | 575/1521 - (37%) |
- Green bases have known domain annotations that are detailed below.
Human 2 ASSNPPP-----QPAIGDQLVPGVPGPSSEAEDDPGEAFEFDDSDDEEDTSAALGVPSLAPERDT 61
Human 62 DPPLIHLDSIPVTDPDPAAAPPGTGVPAWVSNGDAADAAFSGARHSSWKRKSSRRIDRFTFPALE 126
Human 127 EDVI---YDDVPCESP---------------DAHQPGAERNLLYE--------DAHRAGAPRQAE 165
Human 166 DLGWSSSEFESYSEDSG-----------EEAKPEV-------EVEPAKHRVSFQPKLSPDLTRLK 212
Human 213 E-------------RYARTKRDILALRVG-------------------GRDMQELKHKYDCKMT- 244
Human 245 QLMKAAKSG----TKDGLEKTRMAVMRKVSFLHRKDVLGDSEEED------------MGLLEVSV 293
Human 294 SDIKP-------PA-------------------PELGPMPEGLSPQQVVRRHILGSIVQSEGSYV 332
Human 333 ESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCHSMFQIA--LSSRVAEWDSTEKIGD 395
Human 396 LFVAS---FSK-SMVLDVYSDYVNNFTSA-MSIIKKACLTKPAFLEFLKRRQV--CSPDRVTLYG 453
Human 454 LMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTELETLAEKLNEQKRLADQVAEIQQLTK 518
Human 519 SVSDRSSLNKLLTSGQRQLLL-----------CETLTETVYGDR-----------GQLIK----- 556
Human 557 -----------SKERRVFLLNDMLVCANINFKPANHRGQLEISSLVPLGPKYVVKWNTALPQVQV 610
Human 611 VEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGPPRLFQELQDLQKDLAVVEQITLLIST 675
Human 676 LHGT-----------------YQNLNMTVAQDWCLALQRL--MRVKEEE-----------IHSA- 709
Human 710 -------------------------------NKCRLRLLLPGKPDKSGRPISFMVVFITPNPLSK 743
Human 744 ISWV--------NRLHLAKIGLREEN-----QPGWLCPDEDKKSKAPFWCPILACCIPAFSSRAL 795
Human 796 SLQL----GALVHSP--VNCPLLGFSAVSTSLPQGYLWVGGGQEGAGGQV-EIFSLNRPSPRTVK 853
Human 854 SFPLAAPVL--CMEYIPELEEEAESRDESPTVADP--------SATVHPTICLGLQDGSILLYSS 908
Human 909 VDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGVLWDLESPPVCLTVGPGP 973
Human 974 VRTLLS------LEDAVWASCGPRVT------VLEATTLQPQQSFEAHQDEAVSVTHMVKAGSGV 1026
Human 1027 WMAFSSGTSIRLFHTETLEHLQ-EINIATRTTFLLPGQKHLCVTSLLICQGLLWVGTDQGVIVLL 1090
Human 1091 PVPR--------------------LEGIPKIT------------GKGMVSLNG------------ 1111
Human 1112 --HC--------------------------GP---------------VAFLAVATSILAPDILRS 1133
Human 1134 DQEEAEGPRAEEDKPDGQAHEPMPDS 1159 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ARHGEF10L | NP_060595.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..91 | 19/93 (20%) | |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 159..197 | 7/55 (13%) | |||
RhoGEF | 317..501 | CDD:238091 | 41/192 (21%) | ||
WD40 repeat | 927..970 | CDD:293791 | 6/42 (14%) | ||
WD40 repeat | 978..1007 | CDD:293791 | 11/40 (28%) | ||
WD40 repeat | 1016..1046 | CDD:293791 | 3/29 (10%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1135..1163 | 9/25 (36%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1186..1208 | ||||
PsGEF | NP_996333.4 | DUF4799 | <102..209 | CDD:292674 | |
C2 | 286..>381 | CDD:278593 | |||
PDZ_signaling | 644..716 | CDD:238492 | 11/71 (15%) | ||
RhoGEF | 831..1000 | CDD:295373 | 41/198 (21%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3522 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |