DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PPP2CB and PpV

DIOPT Version :9

Sequence 1:NP_001009552.1 Gene:PPP2CB / 5516 HGNCID:9300 Length:309 Species:Homo sapiens
Sequence 2:NP_001259272.1 Gene:PpV / 31582 FlyBaseID:FBgn0003139 Length:303 Species:Drosophila melanogaster


Alignment Length:301 Identity:164/301 - (54%)
Similarity:215/301 - (71%) Gaps:0/301 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGG 73
            ::|:|:|.:.:||.|.||:::.|||...:||.:|:|:..|..|||||||:||||:||.:|||.||
  Fly     3 DVDKWIEDVKKCKYLPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDLEQLFRTGG 67

Human    74 KSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYG 138
            :.|.|||:||||:|||||||:||.|.|:.||.|||.|||:||||||:||||:||||:|||..|||
  Fly    68 QVPHTNYIFMGDFVDRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSKYG 132

Human   139 NANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDP 203
            |||.|||...:||.|.:.|::|.::.|:||||||.|.|||.||.:||..|:|::|..|||:||||
  Fly   133 NANGWKYCCKVFDLLTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAFCDLVWSDP 197

Human   204 DDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYR 268
            :|...||.||||||:.||.::::.|...|.|.|:.||||||.||..:..|..:||::||||||||
  Fly   198 EDMEYWGQSPRGAGWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMFDGKLVTVWSAPNYCYR 262

Human   269 CGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 309
            |||.|||:..:...|.....|...|........:.|..|||
  Fly   263 CGNVAAILSFETAEKRQTKIFLAVPDAERVIPKQNTTPYFL 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PPP2CBNP_001009552.1 MPP_PP2A_PP4_PP6 9..293 CDD:277360 159/283 (56%)
PpVNP_001259272.1 PTZ00239 3..303 CDD:173488 162/299 (54%)
MPP_PP2A_PP4_PP6 3..287 CDD:277360 159/283 (56%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53795
OrthoDB 1 1.010 - - D349967at33208
OrthoFinder 1 1.000 - - FOG0000018
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.830

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