Protein Alignment MSTO1 and DML1

DIOPT Version :10

• Sequence 1: NP_060586.2
• Gene: MSTO1 / 55154
• HGNCID: 29678
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_013938.1
• Gene: DML1 / 855251
• SGDID: S000004824
• Length: 475
• Species: Saccharomyces cerevisiae
• Alignment Length: 598
• Identity: 114/598 - (19%)
• Similarity: 199/598 - (33%)
• Gaps: 176/598 - (29%)

Human     7 EVLTLQLGHFAGFVGAHWWNQQDAAL-----GRATDSKEPPGELCPDVLYRTGRTLHGQETYTPR 66
            ||:|:.:...|..:...::|.|:..|     .:..|||    .....|:.:..:|:    :|.||
Yeast     3 EVVTISVSQRANHLTTQFFNIQEGYLQLSKEQQVNDSK----IFLNSVVDKVSKTI----SYAPR 59

Human    67 LILMDLKGSLSSLKEEGGLYR------------DKQLDAAIAWQGKLTTHKEELYPKNPYLQDFL 119
            .:|.|.:....||    |.|:            ||..:..:     :.||..  .||:.| |..|
Yeast    60 ALLWDARTGNGSL----GTYQYSESQDYHFGNEDKFKEQTV-----IKTHPR--IPKSEY-QSSL 112

Human   120 SAEGVLSSDGVWRVKSIPNGKGSSPLPTATTPKPLIPTEASIRVWSDFLRVHLHPRSICMIQKYN 184
            .|                    .:|||.......:        .|||:.::...|.|..:::.:.
Yeast   113 DA--------------------GAPLPCLNRENTM--------YWSDYSKLIYGPSSFNILRNWY 149

Human   185 HDGE-----------AGRLEAFGQGESVLKEPKYQEELEDRLHFYVEECDYLQGFQILCDLHDGF 238
            ||.|           ..:.:.:..|.....|...||..:..||..:|:||.||||.::.|:..|:
Yeast   150 HDTENPNQPDFQNLGERKFDRYSIGYDEFTENYLQEFFDGNLHRELEKCDTLQGFNLVSDMESGW 214

Human   239 SGVGAKAAELLQDEYSGRGIITWGLLPGPYHRGEAQRNIYRLLNTAFGLVHLTAHSSLVCPLSLG 303
            .|..:.....|::|...:.:.:||      |..:..      ....|.:..|:.....:....|.
Yeast   215 GGFSSALLVELRNELPKKAVFSWG------HNEDDP------FTDDFPMKRLSKKWLPIISNKLR 267

Human   304 GSLGLRPEPPVSFPYLHYDATLPFHCSAILATALDTV--TVPYRLCSSPVSMVHL--ADMLSFCG 364
            .::.:..|..:.||.........:..:.......|::  |:.........:|.:|  |..|.:..
Yeast   268 STINMMQESDLYFPLYAAPGLTNWETAGKSCRIFDSINATISQSNLEQRKTMDYLTTAITLGYSS 332

Human   365 KKVVTAGAIIPFPLAPGQSLPDSLMQFGGATPWT------PLSACGEPSGTRCFAQSVVLRGIDR 423
            :.:|| |.:|                  |.|.::      |.....:|:.|..|::|.:.||...
Yeast   333 RNMVT-GMVI------------------GDTDYSFCSRVLPFKNSHKPNSTHIFSKSFIDRGNQT 378

Human   424 ACHTSQLTPGTPPPSALHACTTGEEILAQYLQQQQPGVMSSSHLLLTPCRVAPPYPHLFSSCSPP 488
            ..|.|:      |.|.       .:::..|..:..|               :...|..||:....
Yeast   379 HKHHSE------PDSR-------SKMIEMYTHRYFP---------------SDTIPTEFSNDREF 415

Human   489 GMVLDGSPKGAAVESIPVFGALCSSSSLHQTLEALARDLTKLDLRRWASFMDAGVEHD-DVAELL 552
            .:.|:.|.|.                          ||:.|    .|..|:....::| |..||.
Yeast   416 VLELESSEKN--------------------------RDIFK----HWNEFVVRYFKNDSDREELK 450

Human   553 QELQSLAQCYQGG 565
            .||...|..|:.|
Yeast   451 NELSDYASAYESG 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MSTO1	NP_060586.2	misato	6..563	CDD:276964	112/594 (19%)
DML1	NP_013938.1	Tubulin_FtsZ_Cetz-like	2..>290	CDD:471962	69/346 (20%)