Protein Alignment MSTO1 and mst

DIOPT Version :10

• Sequence 1: NP_060586.2
• Gene: MSTO1 / 55154
• HGNCID: 29678
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_523435.1
• Gene: mst / 33119
• FlyBaseID: FBgn0020272
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 594
• Identity: 178/594 - (29%)
• Similarity: 272/594 - (45%)
• Gaps: 67/594 - (11%)

Human     6 REVLTLQLGHFAGFVGAHWWNQQDAALGRATDSKEPPGELCP--DVLYRTGRTLHGQETYTPRLI 68
            ||:||.|.|.:|.:||.|:||||:|......:|::...|..|  |:|||.||....:.||||||:
  Fly     5 REILTFQFGTYANYVGTHFWNQQEANFRYGDESEQVAEEQLPNNDILYREGRNDLNRTTYTPRLL 69

Human    69 LMDLKGSLSSLKEEGGLYRDKQLDAAIAWQGKLTTHKEELYPKN-----PYLQDFLSAEGVLSSD 128
            .:||.|:|..|...|.||            |......|||.|.:     ..::......||.|.:
  Fly    70 SVDLSGTLGHLPVTGELY------------GNFVQRDEELLPLSTGEELEQVRKRAEESGVCSPE 122

Human   129 GVWRVKSIPNGKGS------SPLPTATTPKPLIPTEASIRVWSDFLRVHLHPRSICMIQKYNHDG 187
               :::.....|.|      ..|..|..|:......|:...|.|||....|||::.::.....|.
  Fly   123 ---QLEVQEQSKASISEYQRDLLKNAVVPEKNYQLAATANSWVDFLYARYHPRTLNVLPGLIRDP 184

Human   188 EAGRLEAFGQGESVLKEPKYQEELEDRLHFYVEECDYLQGFQILCDLHDGFSGVGAKAAELLQDE 252
            .|..|..:..|..:.:|..:.||..||:..||||||.||||.:|.|:.|||.|:..|..|.|.||
  Fly   185 TAQALGTYSAGTEMWQEVSFNEEFCDRIRLYVEECDGLQGFHVLFDIDDGFGGLAGKCLEHLNDE 249

Human   253 YSGRGIITWGLLPGPYHR----GEAQRNI---YRLLNTAFGLVHLTAHSSLVCPLSL------GG 304
            ||....    .||..|.|    .:|...:   .|::|...|...|:..:.:..|||.      ..
  Fly   250 YSRASF----ALPLHYPRITSYPQADTRLSHSIRVVNNVLGYHQLSEQALMFTPLSTLETIWRNN 310

Human   305 SLGLRPEPPVSFPYLHYDATLPFHCSAILATALDTVTVPYRLCSSPVSMVHLADMLSFCGKKVVT 369
            :|..|     |.|.|.::....:..||:||...||.|:.|||..:|.|::...:.::..|:|:..
  Fly   311 NLKSR-----SLPGLQWETDNLYQTSALLAAFFDTATLSYRLRQTPESLLRFCECVTPAGRKMTA 370

Human   370 AGAIIPFPLAPGQSLPDSLMQFGGATPWTPLSACGEPSGTRCFAQSVVLRGI--DRACHTSQLTP 432
            ||..:||.|..||.|.:.|.|.|.....|.|:...|| ||....|||..|||  :|.....:|.
  Fly   371 AGLALPFGLREGQDLIEFLDQSGDHALLTQLTPGCEP-GTSYVVQSVTARGIPAERLKRPRELA- 433

Human   433 GTPPPSALHACTTGEEILAQYLQQQQPGVMSSSHLLLTPCRVAPPYPH-LFSSCSPPGMVLDG-- 494
            |.....|.::|.:...:|..|.|....|.::::.....|.:...|:|: :|::    |:..||
  Fly   434 GDQLRMAAYSCDSISHMLQLYYQCTYHGSVTNAAATPLPLKTQLPFPYEMFAA----GISRDGYR 494

Human   495 SPKGA------AVESIPVFGALCSSSSLHQTLEALARDLTKLDLRRWASFMDAGVEHDDVAELLQ 553
            .|:||      .|:|.|:..|:.:|:.|.:.|:.:.....::.|.:..::.::|:|.|:....|.
  Fly   495 LPEGAERETGSRVDSAPMLAAVQNSTKLGEHLDNVHAQSHRVQLAKLQAYSNSGLERDEYDTALD 559

Human   554 ELQSLAQCY 562
            :|......|
  Fly   560 QLLEFRDLY 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MSTO1	NP_060586.2	misato	6..563	CDD:276964	178/594 (30%)
mst	NP_523435.1	misato	5..570	CDD:276964	178/594 (30%)