Protein Alignment MSTO1 and dml1

DIOPT Version :10

• Sequence 1: NP_060586.2
• Gene: MSTO1 / 55154
• HGNCID: 29678
• Length: 570
• Species: Homo sapiens
• Sequence 2: NP_594658.1
• Gene: dml1 / 2542590
• PomBaseID: SPAC30C2.06C
• Length: 465
• Species: Schizosaccharomyces pombe
• Alignment Length: 601
• Identity: 117/601 - (19%)
• Similarity: 196/601 - (32%)
• Gaps: 191/601 - (31%)

Human     7 EVLTLQLGHFAGFVGAHWWNQQDAAL---------------GRATDSKEP------PGELCPDVL 50
            |:||:..|..:.|...|:||.|::..               .|....::|      |.|...|..
pombe     3 EILTVTFGRKSNFCWTHFWNTQESYFVYDPNDHAKVNVNTNFRVLKKRDPEAIVTVPRECIYDTP 67

Human    51 YRTGRTLHGQETYTPRLILMDLKGSLSSLKEEGGLYRDKQLDAAIAWQGKLTTHKEELYPKNPYL 115
            ...|.|               .|..|..|.|..|       ....||.||||...:.....:||
pombe    68 IEFGNT---------------RKNWLEELNESSG-------GKGTAWDGKLTQIMQTPVDVHPY- 109

Human   116 QDFLSAEGVLSSDGVWRVKSIPNG---KGSSPLPTATTPKPLIPTEASIRVWSDFLRV-----HL 172
                       .:.:|....|..|   :....|| :..||       |::.||||.|:     :|
pombe   110 -----------QEALWSRDEIHEGNAIESEYELP-SIRPK-------SVKYWSDFNRLFLDTEYL 155

Human   173 HPRSICMIQKYNHDGEAGRLEAFGQGESVLKEPKYQEELEDRLHFYVEECDYLQGFQILCDLHDG 237
            .|.:...:...:...:.| :|.|...:      |.....::.|...|||||.:||||...|:...
pombe   156 FPVNCSELNSSDFSFQLG-VERFHDFD------KQFNVWDEGLRPLVEECDSVQGFQAAIDIDTP 213

Human   238 FSGVGAKAAELLQDEYSGRGIITW--GLL-PGPYHRGEAQRNIYRLLNTAFGLVHLTAHSSL--- 296
            :.|..::..:::|||.....:.||  |:. |..........|.:..||.|..|..|....|.
pombe   214 WGGFASEYMKVVQDELGECRVPTWVYGIREPIQSDSSATIDNHFGKLNEALSLSQLNGSCSQYFP 278

Human   297 VCPLSLGGSLGLRPEPPVSFPYLHYDATLPFHCSAILATALDTVTVPYRLCSSPVSMVHLADM-- 359
            :|.:|.|..|                    :..||.:..|:::.|:|.|:..|  |...:.|:
pombe   279 LCTISQGDDL--------------------WASSAKINLAIESFTLPTRVYGS--SCYRMKDIES 321

Human   360 ------------LSFCGKKVVTAGAIIPFPLAPGQSLPDSLMQFGGATPWTPLSACGEPSGTRCF 412
                        |:|..|..                         .:..|..:|:....:..:.:
pombe   322 KLQSEGRGFIHNLNFKAKNY-------------------------SSKEWALVSSASFVNVAQDY 361

Human   413 A-QSVVLRGIDRACHTSQLTPGTPPPSALHACTTGEEILAQYLQQQQPGVMSSSHLLLTPCRVAP 476
            : |:..|.|:.|:...:|        ..|.........:::.:..|..|:.|
pombe   362 SQQNNCLFGVVRSPKDNQ--------GLLEGKNYNASSISKIVNIQNLGLPS------------- 405

Human   477 PYPHLFSSCSPPGMVLDGSPKGAAVESIPVFGALCSSSSLHQTLEALARDLTKLDLRRWASFMDA 541
                           |:..|:|..... .||....:...::..::.|.:.|.    ||:.||:|
pombe   406 ---------------LETVPEGLRTLD-TVFVEATNDGQINSHIQGLTKSLN----RRFVSFVD- 449

Human   542 GVEHDDVAELLQELQS 557
               .|::.|:.:.|.|
pombe   450 ---QDELEEIREILSS 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MSTO1	NP_060586.2	misato	6..563	CDD:276964	117/601 (19%)
dml1	NP_594658.1	Tubulin_FtsZ_Cetz-like	2..>332	CDD:471962	87/399 (22%)