Protein Alignment ELP3 and Elp3

DIOPT Version :10

• Sequence 1: NP_060561.3
• Gene: ELP3 / 55140
• HGNCID: 20696
• Length: 547
• Species: Homo sapiens
• Sequence 2: NP_608834.1
• Gene: Elp3 / 33649
• FlyBaseID: FBgn0031604
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 549
• Identity: 452/549 - (82%)
• Similarity: 505/549 - (91%)
• Gaps: 2/549 - (0%)

Human     1 MRQKRK--GDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDIIAA 63
            |:.|:|  ..||..|..:|.||::|::|::|||..||::||::|:..|:||||.:.|||||||||
  Fly     1 MKAKKKLGVGLSRQERQVLVIGEIIQELLKAHEAKKDVNLNRMKSLVASKYGLDSSPRLVDIIAA 65

Human    64 VPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYT 128
            ||...:|:|:|||:|||||||||||||||||||||||||:.||||||||||||||||||||||||
  Fly    66 VPQDAKKILLPKLRAKPIRTASGIAVVAVMCKPHRCPHINMTGNICVYCPGGPDSDFEYSTQSYT 130

Human   129 GYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDAL 193
            |||||||||||:|||||||||||:|||||||||||||||||||||||.|||||||||||||||||
  Fly   131 GYEPTSMRAIRSRYDPFLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMCLPEEYRDYFIRNLHDAL 195

Human   194 SGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDT 258
            |||:|.|:.|||:|||:|.|||||||||||||||:|||:||||:|||||||||||||||||||||
  Fly   196 SGHSSANVAEAVRYSEKSRTKCIGITIETRPDYCLKRHISDMLSYGCTRLEIGVQSVYEDVARDT 260

Human   259 NRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVI 323
            ||||||:||||||.|.||:|:|:|.|||||||||..|||||||.|:|||||||.||||:||||||
  Fly   261 NRGHTVRAVCESFQLGKDAGYKIVTHMMPDLPNVDFERDIEQFIEYFENPAFRSDGLKIYPTLVI 325

Human   324 RGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELAL 388
            ||||||||||:||||||.||.||:|||:|||||||||||||||||||||||||||||||||||||
  Fly   326 RGTGLYELWKTGRYKSYPPSMLVDLVAKILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELAL 390

Human   389 ARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRL 453
            |||||||..|||||||||||||||:|||||::||:|||||||||||||||||||:||||:|||||
  Fly   391 ARMKDLGTTCRDVRTREVGIQEIHNKVRPYEIELIRRDYVANGGWETFLSYEDPEQDILVGLLRL 455

Human   454 RKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKI 518
            ||||.:|||.||.|..|||||||||||||||::|||||||||||||||||||||||||||||.|:
  Fly   456 RKCSPDTFRPELKGECSIVRELHVYGSVVPVNARDPTKFQHQGFGMLLMEEAERIAREEHGSTKL 520

Human   519 AVISGVGTRNYYRKIGYRLQGPYMVKMLK 547
            ||||||||||||||:||:|.||||.|.::
  Fly   521 AVISGVGTRNYYRKMGYQLDGPYMSKSIE 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ELP3	NP_060561.3	ELP3	36..546	CDD:273503	436/509 (86%)
Elp3	NP_608834.1	ELP3	23..548	CDD:273503	443/524 (85%)