Protein Alignment SRBD1 and srbd1

DIOPT Version :10

• Sequence 1: NP_060549.4
• Gene: SRBD1 / 55133
• HGNCID: 25521
• Length: 995
• Species: Homo sapiens
• Sequence 2: XP_021336424.1
• Gene: srbd1 / 100320270
• ZFINID: ZDB-GENE-081107-19
• Length: 982
• Species: Danio rerio
• Alignment Length: 1030
• Identity: 535/1030 - (51%)
• Similarity: 696/1030 - (67%)
• Gaps: 92/1030 - (8%)

Human     5 PR-RAKVQVQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSR----------------- 51
            || .|||..:... .||...|.::::..:.|.:|...|.|:.|..:::
Zfish     5 PRTTAKVYTEPTT-DDEDEDFDDMTANQKYDSEELDEWLPKLKEGKAKEGKVQKGTDGSTEKKKA 68

Human    52 -------KQPPPK-ESKPK--RMPRVKKNAPQISDGSE-VVVVKEELNSSVAIADTALEDRKNKL 105
                   |:|.|| |.||:  |:|:.||..|.....:| :|::|.|            :|.|
Zfish    69 TKRVAKPKEPKPKAERKPRAPRVPKAKKEKPNTEQQNEDMVLLKPE------------QDVK--- 118

Human   106 DTVQTLKTAKTKQKCAAQPHTVRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEEN 170
                 :|..:.....::....|.|..           .::.||..||..|....      ||||.
Zfish   119 -----IKEERLSMNLSSSNVPVPRDN-----------DDVPGEGPSSSQPFFKV------KKEEP 161

Human   171 DDDFTFGQSALKKIKTETYPQGQPVKFPANANSTKEEVEMNWDMVQVLSERTNIEPWVCANIIRL 235
            :|.|||.:...||.||....||:|:|. .:..|..|:::||||.::||:|:..:..|||.||.:|
Zfish   162 NDSFTFEEPVQKKQKTSDAAQGRPIKL-KSTGSVLEDLQMNWDPIRVLAEKAGVAQWVCMNIAQL 225

Human   236 FNDDNTIPFIIRYRKELINNLDADSLREVQQTLEELRAVAKKVHSTIQKIKKEGKMSECLLKAML 300
            ..::|||||::||||||||::|||::|:|||||:|||:||||..|..|.:||||.::..|..|:.
Zfish   226 LEEENTIPFMVRYRKELINHMDADAVRDVQQTLDELRSVAKKSRSVAQTLKKEGVLTSELEMALK 290

Human   301 NCKTFEELEHVSAPYKTGSKGTKAQRARQLGLEGAARALLEKPGELSLLSYIRPDVKGLSTLQDI 365
            ||.|.:|:|||.||||.|||.:||:||::||||..|.|||..|..|:|.:.|:|:.||||:|.::
Zfish   291 NCTTADEIEHVYAPYKKGSKLSKARRAKELGLEPVALALLHSPQTLNLHASIQPNTKGLSSLDEV 355

Human   366 EIGVQHILADMIAKDKDTLDFIRNLCQKRHVCIQSSLAKVSSK---------KVNEKDVDKFLLY 421
            ..|||.|||.||||||:||.::::||.:..|.|.|:::|.:.|         |...||:.||.||
Zfish   356 ATGVQEILAYMIAKDKETLTYVQSLCDRSAVTIHSAVSKTALKEQQSQQADQKSKPKDIAKFSLY 420

Human   422 QHFSCNIRNIHHHQILAINRGENLKVLTVKVNISDGVKDEFCRWCIQNRWRPRSFARPELMKILY 486
            ..|:|:::.|.|||.||||||||||:|||||||.|.||::|||||:..||||:.||:||||.||.
Zfish   421 TDFTCDVQRIQHHQTLAINRGENLKILTVKVNIPDWVKNDFCRWCVNVRWRPKGFAQPELMSILK 485

Human   487 NSLNDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRNLRQLLLTSPVPGRTLMGVDPGYKHGCK 551
            |:..||:||||.|.|.|.:|.|||:.|||||:.||.|||||.||..||.||.:||||||:.||||
Zfish   486 NAAEDSYKRLILPFLNRGYRTKLTASAEKESIAMFVRNLRQRLLMCPVRGRVIMGVDPGFYHGCK 550

Human   552 LAIISPTSQILHTDVVYLHCGQGFREAEKIKTLLLNFNCSTVVIGNGTACRETEAYFADLIMKNY 616
            |||:||||||:||||||||.....|||:|::.|:..::|.|:|||||.|||||||:|||||.:.:
Zfish   551 LAILSPTSQIVHTDVVYLHGPAIEREADKLRQLMFKYSCQTIVIGNGKACRETEAFFADLIKQRF 615

Human   617 FAPLDVVYCIVSEAGASIYSVSPEANKEMPGLDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGM 681
            |:|:||.|||..|||||||||||||.||||.:||||||||||.||||||||||:||:|||||:|.
Zfish   616 FSPMDVSYCITDEAGASIYSVSPEAVKEMPDMDPNLRSAVSIGRRVQDPLAELIKIDPKHIGIGT 680

Human   682 YQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNIIEWREKNGPFINRE 746
            |||||||:||:|.||.||:|||||||||||||||.|:||||||||.||::|:||:||||||.||:
Zfish   681 YQHDVSQSLLRAALDGVVQECVSFVGVDINICSETLMRHIAGLNAGRARSIMEWKEKNGPFFNRD 745

Human   747 QLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQG-KKKS 810
            |||.|||||||||||||||||||.:.:|:..|...|              |.|:..::.. |||.
Zfish   746 QLKLVKGLGPKSFQQCAGFIRINPETVRSIGSGGKE--------------DPEIPQKQTAEKKKV 796

Human   811 KTAVNVLLKPNPLDQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERL 875
            |.:.::....|||||||||||||.||:|||:.|.|:|.::|...::|.|.|.:...|::.:|:.|
Zfish   797 KGSASISNDFNPLDQTCIHPESYSIALRFLTQIAGSLDQMGSSALRQSIESSVRSSGLDVLAKSL 861

Human   876 QTTVHTLQVIIDGLSQPESFDFRTDFDKPDFKRSIVCLEDLQIGTVLTGKVENATLFGIFVDIGV 940
            .||..|||:|:|||:||..||.|.:|::.||||.:|.:.||..|.||||:|.|..|||.||||||
Zfish   862 NTTPETLQLIVDGLTQPPGFDIRQNFEQADFKREVVSMNDLHDGMVLTGRVTNTALFGAFVDIGV 926

Human   941 GKSGLIPIRNVTEAKLSKTKKRRSLGLGPGERVEVQVLNIDIPRSRITLDLIRVL 995
            |:|||||.|.:|..||...::||||.|||||||||:|:|:||.|:||||||||||
Zfish   927 GRSGLIPKRFITPEKLPVDQRRRSLALGPGERVEVRVMNVDIQRNRITLDLIRVL 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRBD1	NP_060549.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..81		19/85 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..165		7/44 (16%)
		Tex	210..989	CDD:441786	470/788 (60%)
srbd1	XP_021336424.1	FinO_conjug_rep	<45..120	CDD:472793	19/94 (20%)
		Tex	200..975	CDD:441786	470/788 (60%)