Protein Alignment TMEM39B and CG13016

DIOPT Version :10

• Sequence 1: NP_060526.2
• Gene: TMEM39B / 55116
• HGNCID: 25510
• Length: 492
• Species: Homo sapiens
• Sequence 2: NP_610929.2
• Gene: CG13016 / 36562
• FlyBaseID: FBgn0033899
• Length: 443
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 141/497 - (28%)
• Similarity: 232/497 - (46%)
• Gaps: 94/497 - (18%)

Human    22 SSGGSSGS--HTSSASVTSVRSRTRSSSGTGLSSPPLATQTVVPLQHCKIPELPVQASILFELQL 84
            ||.|||.|  |.|.|.:.:.:.        |.|..|   .|.:| :|...||....:..|.||.:
  Fly     7 SSDGSSSSETHDSFAHLLATKQ--------GQSQTP---ATAMP-KHIPFPEHATTSEWLSELIM 59

Human    85 FFCQLIALFVHYINIYKTVWWYPPSHPPSHTSLNFHLIDFNLLMVTTIVLGRRFIGSI----VKE 145
            ....:.:..|.:||||:|.||.|.:|  :...:|..|||..|..:..|:..||.|..:    :::
  Fly    60 CAFTMGSAIVQFINIYRTNWWLPQAH--TRHMVNIELIDPYLRYLLLILNTRRLIYCLLLVKIRK 122

Human   146 ASQRGKVSLFRSILLFLTRFTVLTATGWSLCRSL----IHLFRTYSFLNLLFLCYPFGMYI---- 202
            .:::.:         .|.|..:....|..:..||    :.|::.::::.||||.||..:|:
  Fly   123 RNEKSR---------HLIRLGIKYGFGGLVQLSLGFCAMKLYQKHTYILLLFLFYPVVIYLLIFG 178

Human   203 ----PFLQLNCDLRKTSLFNHMASMGPREAVSGLAKSRDYLLTLRETWKQHTRQLYGPDAMPTHA 263
                |||:...:|             |...::.|                           |.|:
  Fly   179 FQLEPFLRTRFEL-------------PGVYINDL---------------------------PVHS 203

Human   264 CCLSPSLIRSEVEFLKMDFNWRMKEVLVSSMLSAYYVAFVPVWFVKNTHYYDKRWSCELFLLVSI 328
            |..:|..||.|||.|:.|||.|.|:::.:|||:|||...||.....:..|...| :.:..::|.:
  Fly   204 CTTNPVNIRDEVETLRHDFNKRFKQLIFTSMLNAYYTGLVPCCLAVSVQYNVLR-AAQHCIIVCL 267

Human   329 STSVILMQHLLPASYCDLLHKAAAHLGCWQKVD--PA-----LCSNVLQHPWTEECMWPQGVLVK 386
            ....:....|.||.|.|.||:|..||||||::|  ||     :.::.|  .|::...:..|.:||
  Fly   268 GAFSLCAVFLYPAKYSDTLHRATLHLGCWQRIDREPAPSQLIVAASAL--TWSKYSSYNHGTVVK 330

Human   387 HSKNVYKAVGHYNVAIPSDVSHFRFHFFFSKPLRILNILLLLEGAVIVYQLYSLMS-SEKWHQTI 450
            |:..:|::.|...||.|.:.||.||:..|..|..|.:.|.:|:.||::.::.||.: |.:||..:
  Fly   331 HNGGLYRSHGMVTVATPGNASHARFYKLFHNPTIIYSTLAILQAAVLLVEIGSLSAESVEWHFVL 395

Human   451 SLALILFSNYYAFFKLLRDRLVLGKAY--SYSASPQRDLDHR 490
            |::.:.|::..|||||:||.|:....|  .::.:|.:....|
  Fly   396 SISFVAFTSMGAFFKLVRDYLITKDLYKAEHAVAPDQPFRQR 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMEM39B	NP_060526.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..54		11/33 (33%)
		Tmp39	51..478	CDD:463038	129/452 (29%)
CG13016	NP_610929.2	Tmp39	29..423	CDD:463038	129/451 (29%)