DRSC/TRiP Functional Genomics Resources

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Protein Alignment PPP1R7 and CG14185

DIOPT Version :9

Sequence 1:NP_002703.1 Gene:PPP1R7 / 5510 HGNCID:9295 Length:360 Species:Homo sapiens
Sequence 2:NP_649175.1 Gene:CG14185 / 40197 FlyBaseID:FBgn0036936 Length:402 Species:Drosophila melanogaster


Alignment Length:241 Identity:56/241 - (23%)
Similarity:104/241 - (43%) Gaps:40/241 - (16%)


- Green bases have known domain annotations that are detailed below.


Human    10 QQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPEEEHELP--VDMETI 72
            ||.|:.|:.:||        :.|:::|.               :|.....|||..||  |.:..:
  Fly    54 QQQQQRMQFNRR--------QLGRRNSF---------------DRDVAIAEEEQHLPAFVHLLPV 95

Human    73 NLDRDAEDVDLNHY--RIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQ----SLRELDLYDNQ 131
            .|.:...:..|:..  |:.:....|.:::|     |..:|....:|..|.    .|:.|||..:.
  Fly    96 VLPQQGPEPTLDELLRRVTQRTDLEAVEQV-----RLRVISYTVSLSRLSLFLPRLQSLDLSGSV 155

Human   132 IKKIENL-EALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGS 195
            :..:.:| ..|.:|..||||...|.:.:|...|..::.|....|.|.:::.|:.|..|::|:..:
  Fly   156 LSSLRDLGYGLLQLTRLDISNCGLNSFDGTSGLPAIRVLIADGNMIQRVDPLAELVHLRVLKARN 220

Human   196 NRIRAIENIDTL---TNLESLFLGKNKITKLQNLDALTNLTVLSMQ 238
            |||..:..:..|   ..|:.:.|..|.:.:|....:|...:|.::|
  Fly   221 NRISELGLLSFLGMCPQLQEVELQGNPVCRLPLYRSLLARSVPTLQ 266

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PPP1R7NP_002703.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..64 12/53 (23%)
LRR 1 77..98 3/22 (14%)
internalin_A 87..>317 CDD:380193 39/160 (24%)
LRR 2 99..120 4/20 (20%)
leucine-rich repeat 100..121 CDD:275380 5/24 (21%)
LRR 3 121..142 5/21 (24%)
leucine-rich repeat 122..143 CDD:275380 6/21 (29%)
LRR 4 143..164 7/20 (35%)
leucine-rich repeat 144..165 CDD:275380 8/20 (40%)
LRR 5 165..186 4/20 (20%)
leucine-rich repeat 166..187 CDD:275380 5/20 (25%)
LRR 6 187..208 6/23 (26%)
leucine-rich repeat 188..209 CDD:275380 6/23 (26%)
LRR 7 209..230 4/20 (20%)
leucine-rich repeat 210..231 CDD:275380 5/20 (25%)
LRR 8 231..252 2/8 (25%)
leucine-rich repeat 232..253 CDD:275380 2/7 (29%)
LRR 9 253..274
leucine-rich repeat 254..275 CDD:275380
LRR 10 275..296
leucine-rich repeat 276..297 CDD:275380
LRR 11 297..318
LRRcap 336..354 CDD:197729
CG14185NP_649175.1 LRR_8 144..201 CDD:290566 16/56 (29%)
leucine-rich repeat 146..168 CDD:275380 6/21 (29%)
LRR_4 168..209 CDD:289563 12/40 (30%)
leucine-rich repeat 169..190 CDD:275380 8/20 (40%)
leucine-rich repeat 191..212 CDD:275380 5/20 (25%)
leucine-rich repeat 213..237 CDD:275380 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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