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Protein Alignment ATG16L1 and GLE2

DIOPT Version :9

Sequence 1:	NP_001350671.1	Gene:	ATG16L1 / 55054	HGNCID:	21498	Length:	624	Species:	Homo sapiens
Sequence 2:	NP_011033.3	Gene:	GLE2 / 856844	SGDID:	S000000909	Length:	365	Species:	Saccharomyces cerevisiae

Alignment Length:	267	Identity:	66/267 - (24%)
Similarity:	112/267 - (41%)	Gaps:	62/267 - (23%)

- Green bases have known domain annotations that are detailed below.

Human   380 SGSNAGITSIEFDSAGSYLLAASN-DFASRIWTVDD----YRLRHTLTGHSGKVLSAKFLLDNAR 439
            |.:...|:.|.|.....::.:||: |...|||.|.:    .|.:|.   .|..||..::..|..:
Yeast    33 SPAEDSISDIAFSPQQDFMFSASSWDGKVRIWDVQNGVPQGRAQHE---SSSPVLCTRWSNDGTK 94

Human   440 IVSGSHDRTLKLWDLRS-------------KVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFW 491
            :.||..|..|||:|:.|             || ::.|..|.|      ..:|:::|.:||.|::|
Yeast    95 VASGGCDNALKLYDIASGQTQQIGMHSAPIKV-LRFVQCGPS------NTECIVTGSWDKTIKYW 152

Human   492 DIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLR--TNAIKQTFSAPGFKCGSDW 554
            |:|....|..:.:..::.::|  .:::.|:..:.:..:.:|:|.  |...|.|.|.      ..|
Yeast   153 DMRQPQPVSTVMMPERVYSMD--NKQSLLVVATAERHIAIINLANPTTIFKATTSP------LKW 209

Human   555 -TRVVF---SPDGSYVAAGSAEGSLYIWSVLTGKVEK--VLSKQHSSS----------------I 597
             ||.|.   ..||  .|.||.||...|..:..|..:|  ...|.|..:                :
Yeast   210 QTRCVACYNEADG--YAIGSVEGRCSIRYIDDGMQKKSGFSFKCHRQTNPNRAPGSNGQSLVYPV 272

Human   598 NAVAWSP 604
            |::|:.|
Yeast   273 NSIAFHP 279

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.