DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment iglon5 and DIP-epsilon

DIOPT Version :9

Sequence 1:	NP_001017775.2	Gene:	iglon5 / 550472	ZFINID:	ZDB-GENE-050417-297	Length:	332	Species:	Danio rerio
Sequence 2:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	304	Identity:	92/304 - (30%)
Similarity:	143/304 - (47%)	Gaps:	40/304 - (13%)

- Green bases have known domain annotations that are detailed below.

Zfish    28 EFGHLPDNITVLEGESVVLRCKIDEEVTHK-AWLN--RSNILFTGTDKWSLDSRVSL---ENNNN 86
            ||..:.:||||..|.:|.|.|.:....::| ||::  :|.||.......:.:.|:|:   :::.:
  Fly    53 EFTDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKH 117

Zfish    87 SDFSIRIERVMVADEGPYTCSFQARNKPRTAHVYLIVQVPARIVN--ISQDKSVNEGEDVNLFCL 149
            ..:.:.|..|...|.|.|.|...... .:|.:.::.|.||..|.:  .|.|..|.||::|.|.|.
  Fly   118 RTWFLHINNVQEEDRGRYMCQINTVT-AKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCK 181

Zfish   150 AVGRPEPTITWK--DFKYGLLN--------EGEFLEITEIKRHQAEDFECITNNGVAPPDTRKVK 204
            |.|.|||||.||  |....::|        |.:.||:..|.|.....:.||.:|||.|..::::|
  Fly   182 AKGSPEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRIK 246

Zfish   205 VTVNYPPIITDVKNMPAQ-----VGKTAILRCEAMAVPTASFEWYRD-DRRPVESDNTLKIKNE- 262
            |:|::.|::.    :|.|     :|....|.|...|.||:...|.|: |:...||.   |.|.|
  Fly   247 VSVDFSPMVW----IPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESS---KYKTET 304

Zfish   263 -------KTRSLLLFTNVTEKHFGNYTCFASNRLGASNASMLLF 299
                   |....|..|||....:|||.|.|.|..|..:.::.|:
  Fly   305 IPGHPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLY 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
iglon5	NP_001017775.2	IG_like	33..123	CDD:214653	23/95 (24%)
		Ig	35..123	CDD:299845	23/93 (25%)
		Ig	125..>183	CDD:299845	27/69 (39%)
		I-set	128..207	CDD:254352	33/90 (37%)
		IG_like	217..298	CDD:214653	28/94 (30%)
		ig	223..296	CDD:278476	26/81 (32%)
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	24/96 (25%)
		Ig	69..139	CDD:143165	17/69 (25%)
		IG_like	165..249	CDD:214653	32/83 (39%)
		IGc2	172..237	CDD:197706	24/64 (38%)
		IG_like	267..348	CDD:214653	26/83 (31%)
		Ig	270..339	CDD:299845	24/71 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576315
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850