Protein Alignment PPP1CC and Pp1-Y1

DIOPT Version :10

• Sequence 1: XP_011536806.1
• Gene: PPP1CC / 5501
• HGNCID: 9283
• Length: 362
• Species: Homo sapiens
• Sequence 2: NP_001104152.3
• Gene: Pp1-Y1 / 5740113
• FlyBaseID: FBgn0261399
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 293
• Identity: 173/293 - (59%)
• Similarity: 222/293 - (75%)
• Gaps: 3/293 - (1%)

Human     9 IDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLL 73
            :|.:|..||   ..|..:.:.:.|::|..|..::|::.:|:|:||.:|||:.:.|||||||.|||
  Fly    17 LDEMIASLL---SWKIDRKMMVPESDIIKLLKQARQVLMSEPMLLTVEAPVNVLGDIHGQYNDLL 78

Human    74 RLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYD 138
            |.||..|.||:..||.|||||||||.|:||:.||||||::||.:..|||||||.|:|||.|||||
  Fly    79 RYFETSGHPPKKRYLMLGDYVDRGKYSVETLTLLLAYKVRYPTSIHLLRGNHESAAINRYYGFYD 143

Human   139 ECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCD 203
            |||||:.|:||:.|.||::|||:|||::.|||||||||||.|.::..|:.:.||.:|...|||||
  Fly   144 ECKRRFTIRLWRMFVDCYDCLPVAAIINSKIFCCHGGLSPSLHNLNDIQHLQRPAEVDRNGLLCD 208

Human   204 LLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268
            |||||||...:||.:|.||||||||.::|..||.:...||||||||||||||||||||||:|:||
  Fly   209 LLWSDPDPTAIGWEKNSRGVSFTFGVDIVETFLSRFSFDLICRAHQVVEDGYEFFAKRQLITVFS 273

Human   269 APNYCGEFDNAGAMMSVDETLMCSFQILKPAEK 301
            |.|||||||||||||.||..|..:..::||.::
  Fly   274 AVNYCGEFDNAGAMMCVDAELNITLVVMKPKKR 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP1CC	XP_011536806.1	MPP_PP1_PPKL	8..298	CDD:277359	171/288 (59%)
Pp1-Y1	NP_001104152.3	MPP_superfamily	17..303	CDD:472684	171/288 (59%)