Protein Alignment PPP1CC and CanA1

DIOPT Version :10

• Sequence 1: XP_011536806.1
• Gene: PPP1CC / 5501
• HGNCID: 9283
• Length: 362
• Species: Homo sapiens
• Sequence 2: NP_524600.3
• Gene: CanA1 / 43670
• FlyBaseID: FBgn0010015
• Length: 622
• Species: Drosophila melanogaster
• Alignment Length: 307
• Identity: 113/307 - (36%)
• Similarity: 175/307 - (57%)
• Gaps: 29/307 - (9%)

Human     6 KLNIDSIIQR-LLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQY 69
            |.|.|::.|. |||.|         ::|.....:..:...:...:..::::|||:.:|||||||:
  Fly    80 KPNFDALRQHFLLEGR---------IEEAVALRIITEGAALLREEKNMIDVEAPITVCGDIHGQF 135

Human    70 YDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIY 134
            :||::|||.||.|..:.|||||||||||..|:|.:..|.:.||.||....||||||||..:...:
  Fly   136 FDLVKLFEVGGPPATTRYLFLGDYVDRGYFSIECVLYLWSLKITYPTTLSLLRGNHECRHLTEYF 200

Human   135 GFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQG 199
            .|..||..:|:..::....:.|:|||:||:::::..|.||||||::.:::.|:.:.|..:.|..|
  Fly   201 TFKQECIIKYSESIYDACMEAFDCLPLAALLNQQFLCIHGGLSPEIFTLDDIKTLNRFREPPAYG 265

Human   200 LLCDLLWSDPDKDVLGWGEND-------RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEF 257
            .:||||||||.:|......|:       ||.|:.|......:||.|::|..|.|||:..:.||..
  Fly   266 PMCDLLWSDPLEDFGNEKTNEFFSHNSVRGCSYFFSYSACCEFLQKNNLLSIVRAHEAQDAGYRM 330

Human   258 FAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM------CS 292
            :.|.|      |:|:||||||...::|..|::..:..:|      ||
  Fly   331 YRKNQVTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP1CC	XP_011536806.1	MPP_PP1_PPKL	8..298	CDD:277359	112/305 (37%)
CanA1	NP_524600.3	MPP_PP2B	81..385	CDD:277361	112/306 (37%)