DRSC/TRiP Functional Genomics Resources

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Protein Alignment PPP1CC and CG11597

DIOPT Version :9

Sequence 1:XP_011536806.1 Gene:PPP1CC / 5501 HGNCID:9283 Length:362 Species:Homo sapiens
Sequence 2:NP_001036602.1 Gene:CG11597 / 39337 FlyBaseID:FBgn0036212 Length:317 Species:Drosophila melanogaster


Alignment Length:311 Identity:131/311 - (42%)
Similarity:187/311 - (60%) Gaps:14/311 - (4%)


- Green bases have known domain annotations that are detailed below.


Human     1 MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDI 65
            |.|.|:|     ::.|..|....|      :|.|:|.||....::.:.:..||.|::|..:||||
  Fly    10 MNDADRL-----VENLRHVPVRLP------RELEVRQLCRSLSDLLVGESNLLSLQSPQIVCGDI 63

Human    66 HGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI 130
            |||:.|||.|.|.||...|..||||||.|||||.|:||..||.|.|:::|....||||||||.|.
  Fly    64 HGQFEDLLHLLELGGSVQEHRYLFLGDLVDRGKNSVETFLLLAALKVRHPAQVSLLRGNHECRSA 128

Human   131 NRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTD 194
            .|.||||:||..|| :..:|:.....|:.||:|||:|..|.|.|||||||:|.::.:|.:.|..:
  Fly   129 TRSYGFYEECLSRYGSANVWRMCCRVFDLLPLAAIIDGNILCVHGGLSPDMQRLDDLRSLDRCHE 193

Human   195 VPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFA 259
            :|:.|::.||||||| ::..||..:.||....||.:||.:|...:.:.|||||||:.:||:.:..
  Fly   194 IPESGIIADLLWSDP-QEAPGWAASPRGHGKLFGGDVVEEFTRANGISLICRAHQLAQDGFRWHF 257

Human   260 KRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILK-PAEKKKPNATRP 309
            .:.|||::||||||....|..|::.::......|::.: .|...||...:|
  Fly   258 GQLLVTIWSAPNYCYRCGNKAAILRLNAAGDYDFKVFEAQALHSKPQPRKP 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PPP1CCXP_011536806.1 PTZ00480 6..315 CDD:185658 128/306 (42%)
MPP_PP1_PPKL 8..298 CDD:277359 123/291 (42%)
CG11597NP_001036602.1 PTZ00239 12..307 CDD:173488 129/306 (42%)
MPP_superfamily 12..296 CDD:301300 126/295 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53795
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000018
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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