DRSC/TRiP Functional Genomics Resources

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Protein Alignment PPP1CC and Pp2B-14D

DIOPT Version :9

Sequence 1:XP_011536806.1 Gene:PPP1CC / 5501 HGNCID:9283 Length:362 Species:Homo sapiens
Sequence 2:NP_001245715.1 Gene:Pp2B-14D / 32624 FlyBaseID:FBgn0011826 Length:570 Species:Drosophila melanogaster


Alignment Length:321 Identity:116/321 - (36%)
Similarity:177/321 - (55%) Gaps:37/321 - (11%)


- Green bases have known domain annotations that are detailed below.


Human     9 IDSI---------IQRLLEVRGSKPGKNVQLQENEIRG---------LCLKSREIFLSQPILLEL 55
            :||:         :..:.:.|..||...:..|...:.|         :......:...:..::::
  Fly    83 VDSVPFPPSHKLTLAEVFDQRTGKPNHELLKQHFILEGRIEEAPALKIIQDGAALLRQEKTMIDI 147

Human    56 EAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 120
            |||:.:|||||||:|||::|||.||.|..:.|||||||||||..|:|.:..|.:.||.||:..||
  Fly   148 EAPVTVCGDIHGQFYDLMKLFEVGGSPASTKYLFLGDYVDRGYFSIECVLYLWSLKITYPQTLFL 212

Human   121 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 185
            |||||||..:...:.|..|||.:|:.:::....|.|:|||:||:::::..|.||||||::..:|.
  Fly   213 LRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIHELED 277

Human   186 IRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGEND-------RGVSFTFGAEVVAKFLHKHDLDL 243
            |||:.|..:.|..|.:||||||||.:|......:|       ||.|:.:.......||..::|..
  Fly   278 IRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGCSYFYSYAACCDFLQNNNLLS 342

Human   244 ICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM------CS 292
            |.|||:..:.||..:.|.|      |:|:||||||...::|..|::..:..:|      ||
  Fly   343 IIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PPP1CCXP_011536806.1 PTZ00480 6..315 CDD:185658 116/321 (36%)
MPP_PP1_PPKL 8..298 CDD:277359 116/321 (36%)
Pp2B-14DNP_001245715.1 MPP_PP2B 107..411 CDD:277361 112/297 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53795
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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