Protein Alignment myot and zormin

DIOPT Version :10

• Sequence 1: NP_001017159.2
• Gene: myot / 549913
• XenbaseID: XB-GENE-955641
• Length: 497
• Species: Xenopus tropicalis
• Sequence 2: NP_001261317.1
• Gene: zormin / 2769001
• FlyBaseID: FBgn0052311
• Length: 3664
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 117/516 - (22%)
• Similarity: 189/516 - (36%)
• Gaps: 103/516 - (19%)

 Frog    32 KCQVESTSQSTNEAVHTSRSPKKISISIQPQPCSSYNMSSAAPVAPSKCSKTEV-HLQPQSSNIA 95
            |.||:...:|.|:|.......:||....:.   .||..:|.:...|......|. :|.....|..
  Fly  1084 KDQVKQKRKSLNQATDFFEVVEKIDAEYRE---ISYFYTSVSNKVPYLRDSVEAGNLVNDIENYV 1145

 Frog    96 LSGQENDQSKNTSTAFLTISPSKSQS-------------KPKM-INTGTSNLPNASVKTDLRQ-- 144
            .|.:...:||..|.:......:|..|             |.|| ||.....|.....:.:.|:
  Fly  1146 TSREAALRSKLDSASQCAHDMNKVSSLYNDVMNIFQSFIKLKMDINVVQERLKQEQRQKEQRERD 1210

 Frog   145 --DQHEYERGIQGT------------------KDALIQDLERKLKCKDSILHNGNQR------LT 183
              ||.|.|:.|:..                  :.|.|:..:|:|..::..|.....|      ..
  Fly  1211 ARDQAEREKAIKEAEAKERLHREEQSRLENQRQQAAIEQAQRELAARELALREQAVREEEARLQA 1275

 Frog   184 YEEKMARRLLGAENAASVFEDHMADSVQD---------SKQIRDSVTMPSLQQHEKHSRNRESTS 239
            ..|:..|..|..|.||.. |:....|::|         .:.|||..|....::.|:..|..||.|
  Fly  1276 IREQATREQLAREQAARE-EELRIQSLRDIARREEEVRLQNIRDEETRIRREEEERIRRENESRS 1339

 Frog   240 GSIQE-----------------------------------------KYFPPRFLQVPEDLTVEEG 263
            ...:|                                         :|..|.|.:..:|....||
  Fly  1340 KREEEARIQREEITRLQTLRDQVDQQRIVTENIRKDIQVNSIFTELRYASPLFTRPLKDAVSREG 1404

 Frog   264 HFCRIDFKVAGVPVPDVSWYLNGKAVQADDFHKFIVSEKGVHSFIFEVVKTYDAGLYKCVASNRA 328
            .....:.:|.|.|.|.|.|:.:|.::|.:..:| ...:||:...:.|.....|:..:.|.|||..
  Fly  1405 DRFVFECEVTGTPEPAVEWFKDGISIQTNSDYK-TTFDKGICRLVIEETFAADSARFSCRASNLV 1468

 Frog   329 GKSTFTLQLDV---LAQERKRPPCFIQKPAAIKAIEGENIKIECLISAIPQPQILLKKNNEMLRY 390
            |.......|.|   .|:.:..||..::...:.||.||.:.:..|:::.:|.|.:...||::.:..
  Fly  1469 GTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDD 1533

 Frog   391 NTDRIRLYQDDSGRVSLVIYNVNKTDDGWYTISAVNEAGVATCHARLDVATIVNKQMPSVK 451
            :.|.:..|  ::|..:|....|...||..||.||.|.||:..|.|.|.|..:...::||.|
  Fly  1534 SPDYVISY--NNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPTELPSFK 1592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myot	NP_001017159.2	Ig	249..339	CDD:472250	24/89 (27%)
		Ig strand B	266..270	CDD:409582	0/3 (0%)
		Ig strand C	279..283	CDD:409582	1/3 (33%)
		Ig strand E	305..309	CDD:409582	0/3 (0%)
		Ig strand F	319..324	CDD:409582	1/4 (25%)
		Ig strand G	332..335	CDD:409582	0/2 (0%)
		IgI_Myotilin_C	348..439	CDD:409473	27/90 (30%)
		Ig strand A	348..351	CDD:409473	1/2 (50%)
		Ig strand A'	354..359	CDD:409473	0/4 (0%)
		Ig strand B	364..371	CDD:409473	1/6 (17%)
		Ig strand C	378..384	CDD:409473	0/5 (0%)
		Ig strand C'	385..388	CDD:409473	0/2 (0%)
		Ig strand D	395..401	CDD:409473	1/5 (20%)
		Ig strand E	404..414	CDD:409473	2/9 (22%)
		Ig strand F	418..426	CDD:409473	4/7 (57%)
		Ig strand G	428..439	CDD:409473	5/10 (50%)
zormin	NP_001261317.1	SPEC	126..332	CDD:238103
		SPEC	<504..641	CDD:413338
		SMC_prok_B	654..>1389	CDD:274008	59/308 (19%)
		Smc	<1192..>1377	CDD:440809	32/185 (17%)
		I-set	1390..1479	CDD:400151	24/89 (27%)
		Ig strand B	1407..1411	CDD:409564	0/3 (0%)
		Ig strand C	1420..1424	CDD:409564	1/3 (33%)
		Ig strand E	1445..1449	CDD:409564	0/3 (0%)
		Ig strand F	1459..1464	CDD:409564	1/4 (25%)
		Ig strand G	1472..1475	CDD:409564	0/2 (0%)
		I-set	1491..1580	CDD:400151	27/90 (30%)
		Ig strand B	1508..1512	CDD:409353	0/3 (0%)
		Ig strand C	1521..1525	CDD:409353	0/3 (0%)
		Ig strand E	1546..1550	CDD:409353	1/3 (33%)
		Ig strand F	1560..1565	CDD:409353	2/4 (50%)
		Ig strand G	1573..1576	CDD:409353	1/2 (50%)
		I-set	1589..1675	CDD:400151	3/4 (75%)
		Ig strand B	1606..1610	CDD:409353
		Ig strand C	1619..1623	CDD:409353
		Ig strand E	1641..1645	CDD:409353
		Ig strand F	1655..1660	CDD:409353
		Ig strand G	1668..1671	CDD:409353
		I-set	1702..1786	CDD:400151
		Ig strand B	1714..1718	CDD:409353
		Ig strand C	1727..1731	CDD:409353
		Ig strand E	1752..1756	CDD:409353
		Ig strand F	1766..1771	CDD:409353
		Ig strand G	1779..1782	CDD:409353
		I-set	1811..1902	CDD:400151
		Ig strand B	1828..1832	CDD:409353
		Ig strand C	1841..1845	CDD:409353
		Ig strand E	1868..1872	CDD:409353
		Ig strand F	1882..1887	CDD:409353
		I-set	1927..2015	CDD:400151
		Ig strand B	1944..1948	CDD:409353
		Ig strand C	1957..1961	CDD:409353
		Ig strand E	1981..1985	CDD:409353
		Ig strand F	1995..2000	CDD:409353
		Ig strand G	2008..2011	CDD:409353
		Ig	2142..2231	CDD:472250
		Ig strand B	2159..2163	CDD:409353
		Ig strand C	2172..2176	CDD:409353
		Ig strand E	2197..2201	CDD:409353
		Ig strand F	2211..2216	CDD:409353
		Ig strand G	2224..2227	CDD:409353
		I-set	2238..2325	CDD:400151
		Ig strand B	2255..2259	CDD:409353
		Ig strand C	2268..2272	CDD:409353
		Ig strand F	2309..2314	CDD:409353
		PHA03247	<2593..2893	CDD:223021
		I-set	3566..3655	CDD:400151
		Ig strand B	3583..3587	CDD:409353
		Ig strand C	3596..3600	CDD:409353
		Ig strand E	3621..3625	CDD:409353
		Ig strand F	3635..3640	CDD:409353
		Ig strand G	3648..3651	CDD:409353