Protein Alignment PPP1CA and CanA-14F

DIOPT Version :10

• Sequence 1: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_727985.2
• Gene: CanA-14F / 8674098
• FlyBaseID: FBgn0267912
• Length: 584
• Species: Drosophila melanogaster
• Alignment Length: 334
• Identity: 124/334 - (37%)
• Similarity: 189/334 - (56%)
• Gaps: 37/334 - (11%)

Human     1 MSDSEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGK------------NVQLTENEIRGLCLKS 53
            :|..|:: :||:   ....||.||  ||.|..:|.||            ..::.|:....:..:.
  Fly    84 ISTKERV-IDSV---AFPPSRKLT--CADVFDARTGKPQHDVLKQHFILEGRIEESAALRIIQEG 142

Human    54 REIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLL 118
            ..:..::..::::|||:.:|||||||:|||::|||.||.|..:.|||||||||||..|:|.:..|
  Fly   143 ATLLRTEKTMIDIEAPVTVCGDIHGQFYDLMKLFEIGGSPATTKYLFLGDYVDRGYFSIECVLYL 207

Human   119 LAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCC 183
            .:.||.||:..|||||||||..:...:.|..|||.:|:.:::....|.|:|||:||:::::..|.
  Fly   208 WSLKITYPQTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCV 272

Human   184 HGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGEND-------RGVSFTFGAE 241
            ||||||::..:|.|||:.|..:.|..|.:||||||||.:|......:|       ||.|:.:...
  Fly   273 HGGLSPEIHELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGCSYFYSYA 337

Human   242 VVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETL 300
            ....||..::|..|.|||:..:.||..:.|.|      |:|:||||||...::|..|::..:..:
  Fly   338 ACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 402

Human   301 M------CS 303
            |      ||
  Fly   403 MNIRQFNCS 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP1CA	NP_001008709.1	MPP_PP1_PPKL	8..309	CDD:277359	122/327 (37%)
CanA-14F	NP_727985.2	MPP_PP2B	115..419	CDD:277361	110/297 (37%)