Protein Alignment PPP1CA and PpD6

DIOPT Version :10

• Sequence 1: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_524947.1
• Gene: PpD6 / 49780
• FlyBaseID: FBgn0005779
• Length: 336
• Species: Drosophila melanogaster
• Alignment Length: 315
• Identity: 179/315 - (56%)
• Similarity: 238/315 - (75%)
• Gaps: 21/315 - (6%)

Human     1 MSDSE---------KLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREI 56
            :|:||         .|||:.::.:|:...|      :.:|      .:.|.|:|:..||..:||:
  Fly    15 LSNSEANADYRLPGALNLNDLLNKLMSFRR------SKMQ------RLPLLESEVNLLCTLAREL 67

Human    57 FLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAY 121
            ||.:|:||.:.||:::.||||||:||||::.:..|:||::.||||||||||||.|:|||.||||.
  Fly    68 FLDEPMLLNVPAPIRVVGDIHGQFYDLLKILDQCGYPPQTRYLFLGDYVDRGKNSVETITLLLAL 132

Human   122 KIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGG 186
            ::|:|::.:|||||||..|:||:|||:|||||||.:||||||.||:||:|:|||:..:|||||||
  Fly   133 RVKFPKHIYLLRGNHESQSVNRVYGFFDECKRRYTVKLWKTFVDCYNCMPVAAIISHRIFCCHGG 197

Human   187 LSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 251
            |||.|:.:..|..|.|||:||:.||||||||||||:...||..:|||||:.:|.:|:.|||.|:|
  Fly   198 LSPQLKELSNIESIARPTEVPETGLLCDLLWSDPDRYGFGWTSSDRGVSYLYGRDVLEKFLQKND 262

Human   252 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQI 306
            .||:|||||||||||||||||||||:||||||||.:|||||.|.||:.|:.||.|
  Fly   263 FDLVCRAHQVVEDGYEFFAKRQLVTVFSAPNYCGLYDNAGASMGVDKDLVISFDI 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP1CA	NP_001008709.1	MPP_PP1_PPKL	8..309	CDD:277359	175/299 (59%)
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:472684	169/265 (64%)