Protein Alignment PPP1CA and Pp1-13C

DIOPT Version :9

• Sequence 1: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_524921.1
• Gene: Pp1-13C / 48531
• FlyBaseID: FBgn0003132
• Length: 302
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 275/311 - (88%)
• Similarity: 285/311 - (91%)
• Gaps: 11/311 - (3%)

Human     4 SEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEA 68
            :|.|||:|||.||||           |:|:||||||||:|.||||||||||||.|:|||||||||
  Fly     2 AEVLNLESIISRLLE-----------VRGARPGKNVQLSEGEIRGLCLKSREILLAQPILLELEA 55

Human    69 PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 133
            |||||||||||||||||||||||:|||:|||||||||||||||||||||||||||||.|||||||
  Fly    56 PLKICGDIHGQYYDLLRLFEYGGYPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLR 120

Human   134 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIR 198
            ||||||||||||||||||||||.|||||||||||||||:.||||||||||||||||||.||||||
  Fly   121 GNHECASINRIYGFYDECKRRYTIKLWKTFTDCFNCLPVVAIVDEKIFCCHGGLSPDLTSMEQIR 185

Human   199 RIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVE 263
            |||||||||||||||||||||||||..||||||||||||||||||.|||.|||||||||||||||
  Fly   186 RIMRPTDVPDQGLLCDLLWSDPDKDTIGWGENDRGVSFTFGAEVVVKFLQKHDLDLICRAHQVVE 250

Human   264 DGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNK 314
            ||||||||||||||||||||||||||||||||||.|||||||||||.:|.|
  Fly   251 DGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDNTLMCSFQILKPVEKRK 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP1CA	NP_001008709.1	PTZ00480	6..319	CDD:185658	274/309 (89%)
		MPP_PP1_PPKL	8..309	CDD:277359	269/300 (90%)
Pp1-13C	NP_524921.1	PTZ00480	5..299	CDD:185658	272/304 (89%)
		MPP_PP1_PPKL	6..296	CDD:277359	269/300 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147227
Domainoid	1	1.000	395	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D327461at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100222
Panther	1	1.100	-	-	O	PTHR11668
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X337
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.720