Protein Alignment PPP1CA and Pp1-13C

DIOPT Version :10

• Sequence 1: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_524921.1
• Gene: Pp1-13C / 48531
• FlyBaseID: FBgn0003132
• Length: 302
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 275/311 - (88%)
• Similarity: 285/311 - (91%)
• Gaps: 11/311 - (3%)

Human     4 SEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEA 68
            :|.|||:|||.||||           |:|:||||||||:|.||||||||||||.|:|||||||||
  Fly     2 AEVLNLESIISRLLE-----------VRGARPGKNVQLSEGEIRGLCLKSREILLAQPILLELEA 55

Human    69 PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 133
            |||||||||||||||||||||||:|||:|||||||||||||||||||||||||||||.|||||||
  Fly    56 PLKICGDIHGQYYDLLRLFEYGGYPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLR 120

Human   134 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIR 198
            ||||||||||||||||||||||.|||||||||||||||:.||||||||||||||||||.||||||
  Fly   121 GNHECASINRIYGFYDECKRRYTIKLWKTFTDCFNCLPVVAIVDEKIFCCHGGLSPDLTSMEQIR 185

Human   199 RIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVE 263
            |||||||||||||||||||||||||..||||||||||||||||||.|||.|||||||||||||||
  Fly   186 RIMRPTDVPDQGLLCDLLWSDPDKDTIGWGENDRGVSFTFGAEVVVKFLQKHDLDLICRAHQVVE 250

Human   264 DGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNK 314
            ||||||||||||||||||||||||||||||||||.|||||||||||.:|.|
  Fly   251 DGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDNTLMCSFQILKPVEKRK 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP1CA	NP_001008709.1	MPP_PP1_PPKL	8..309	CDD:277359	269/300 (90%)
Pp1-13C	NP_524921.1	MPP_PP1_PPKL	6..296	CDD:277359	269/300 (90%)