Protein Alignment PPP1CA and Pp1alpha-96A

DIOPT Version :10

• Sequence 1: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_524484.1
• Gene: Pp1alpha-96A / 42922
• FlyBaseID: FBgn0003134
• Length: 327
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 289/340 - (85%)
• Similarity: 302/340 - (88%)
• Gaps: 16/340 - (4%)

Human     4 SEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEA 68
            |:.:|:||||.||||           |:|:||||||||:|:|||.||||||||||||||||||||
  Fly     2 SDIMNIDSIISRLLE-----------VRGARPGKNVQLSESEIRSLCLKSREIFLSQPILLELEA 55

Human    69 PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 133
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||||
  Fly    56 PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYAENFFLLR 120

Human   134 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIR 198
            ||||||||||||||||||||||.|||||||||||||||:|||||||||||||||||||.||||||
  Fly   121 GNHECASINRIYGFYDECKRRYTIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLSSMEQIR 185

Human   199 RIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVE 263
            |||||||||||||||||||||||||..||||||||||||||||||.|||.||:.|||||||||||
  Fly   186 RIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVGKFLQKHEFDLICRAHQVVE 250

Human   264 DGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGR 328
            ||||||||||||||||||||||||||||||||||:||||||||||||||.:..|..|..   .||
  Fly   251 DGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKRRFVYPNFGS---SGR 312

Human   329 PITPPR--NSAKAKK 341
            |:||||  |:...||
  Fly   313 PLTPPRGANNKNKKK 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP1CA	NP_001008709.1	MPP_PP1_PPKL	8..309	CDD:277359	271/300 (90%)
Pp1alpha-96A	NP_524484.1	MPP_PP1_PPKL	6..296	CDD:277359	271/300 (90%)