Protein Alignment PPP1CA and PpN58A

DIOPT Version :10

• Sequence 1: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_477384.1
• Gene: PpN58A / 37493
• FlyBaseID: FBgn0025573
• Length: 324
• Species: Drosophila melanogaster
• Alignment Length: 305
• Identity: 188/305 - (61%)
• Similarity: 237/305 - (77%)
• Gaps: 13/305 - (4%)

Human     5 EKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAP 69
            |.:|||.||.:|.....:             |..||::..||..:|.::||:.|.||.|||:.||
  Fly    20 EGINLDQIIAKLKLIGEI-------------GSVVQISVREIEAVCSRAREVLLKQPTLLEIPAP 71

Human    70 LKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRG 134
            :.:.|||||||.:|||.||..|:||:|.||.|||||||||||:||:.||||.|.:||..|:||||
  Fly    72 INLLGDIHGQYLNLLRYFESNGYPPDSVYLLLGDYVDRGKQSIETLTLLLALKARYPTKFYLLRG 136

Human   135 NHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRR 199
            ||||:|||..|||||||||||.:|||:||.||:||||:|||::|.||||||||||.|.||:|||.
  Fly   137 NHECSSINHFYGFYDECKRRYTVKLWRTFVDCYNCLPLAAIIEENIFCCHGGLSPHLFSMQQIRE 201

Human   200 IMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVED 264
            |.||.::|:.||:||:||||||..:.|||.|:||||.|||::||:.|||:..|:||||.||||||
  Fly   202 IRRPIEIPESGLICDILWSDPDLRIMGWGPNERGVSHTFGSDVVSAFLHRFKLNLICRGHQVVED 266

Human   265 GYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKP 309
            ||||||||||:|:|||||||||||||||||.:::.|:|:|::.:|
  Fly   267 GYEFFAKRQLITIFSAPNYCGEFDNAGAMMCINQDLLCTFRVQRP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP1CA	NP_001008709.1	MPP_PP1_PPKL	8..309	CDD:277359	186/300 (62%)
PpN58A	NP_477384.1	MPP_superfamily	23..311	CDD:472684	186/300 (62%)