Protein Alignment PPP1CA and Pp1-Y2

DIOPT Version :10

• Sequence 1: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_001015497.4
• Gene: Pp1-Y2 / 3355173
• FlyBaseID: FBgn0046698
• Length: 313
• Species: Drosophila melanogaster
• Alignment Length: 327
• Identity: 227/327 - (69%)
• Similarity: 266/327 - (81%)
• Gaps: 26/327 - (7%)

Human     4 SEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEA 68
            :|..|:|.:|.|:::..|:              |.:.|||.:||.||.:|||:|:|||:||||.|
  Fly     9 TELNNIDQLILRIIDTRRL--------------KQLNLTETDIRLLCNRSREVFMSQPMLLELSA 59

Human    69 PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 133
            |:|||||||||:.||||||:|||:||.||||||||||||||||:||:||||||||||||||||||
  Fly    60 PVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLR 124

Human   134 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIR 198
            ||||.|.|||||||||||||||.||||:||.||::|:|::||||||||||||||||||.:|.||.
  Fly   125 GNHESAGINRIYGFYDECKRRYTIKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIG 189

Human   199 RIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVE 263
            ::.||.||||:||||||||||||..:.||.:||||||.||||::|.||:|:|..|||||||||||
  Fly   190 QLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICRAHQVVE 254

Human   264 DGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGR 328
            |||||||||||:|:|||||||||||||||||||||||||||.:|||:.|            ||.|
  Fly   255 DGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKK------------PGLR 307

Human   329 PI 330
            .|
  Fly   308 KI 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP1CA	NP_001008709.1	MPP_PP1_PPKL	8..309	CDD:277359	219/300 (73%)
Pp1-Y2	NP_001015497.4	MPP_PP1_PPKL	13..300	CDD:277359	219/300 (73%)