Protein Alignment PPP1CA and PpV

DIOPT Version :10

• Sequence 1: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_511061.1
• Gene: PpV / 31582
• FlyBaseID: FBgn0003139
• Length: 303
• Species: Drosophila melanogaster
• Alignment Length: 297
• Identity: 128/297 - (43%)
• Similarity: 186/297 - (62%)
• Gaps: 16/297 - (5%)

Human    41 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYV 105
            |.|||::.||....:|.|.:..:|.:..|:.:|||||||:|||.:||..||..|.:||:|:||:|
  Fly    17 LPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDLEQLFRTGGQVPHTNYIFMGDFV 81

Human   106 DRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNC 169
            |||..||||...||..|.:||....|||||||...|.::|||:|||..:| |...||.....|:.
  Fly    82 DRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSKYGNANGWKYCCKVFDL 146

Human   170 LPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGV 234
            |.||||:||::.|.||||||::.:::|||.|.|..::|.:|..|||:||||: |::.||::.||.
  Fly   147 LTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAFCDLVWSDPE-DMEYWGQSPRGA 210

Human   235 SFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET 299
            .:.||..|...|:..::|:|||||||:|.:|.::....:|||::||||||....|..|::|
  Fly   211 GWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMFDGKLVTVWSAPNYCYRCGNVAAILS---- 271

Human   300 LMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNS 336
                   .:.|:|.:.|.  |..: |....:.|.:|:
  Fly   272 -------FETAEKRQTKI--FLAV-PDAERVIPKQNT 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP1CA	NP_001008709.1	MPP_PP1_PPKL	8..309	CDD:277359	121/268 (45%)
PpV	NP_511061.1	MPP_PP2A_PP4_PP6	3..287	CDD:277360	125/284 (44%)