Protein Alignment INTS11 and Ints11

DIOPT Version :10

• Sequence 1: XP_011539949.1
• Gene: INTS11 / 54973
• HGNCID: 26052
• Length: 660
• Species: Homo sapiens
• Sequence 2: XP_006239611.1
• Gene: Ints11 / 298688
• RGDID: 1306841
• Length: 629
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 563/666 - (84%)
• Similarity: 572/666 - (85%)
• Gaps: 87/666 - (13%)

Human     1 MPEIRVTPLGACPVLSWNLVLPPGRGSRAPSSTDTRTGFHVLPHGPLGCGPVILMCGAGFGHFEW 65
            |||||||||
  Rat     2 MPEIRVTPL-------------------------------------------------------- 10

Human    66 LAGGGAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHFH 130
                |||||||||||||||:|||||||||||||:||||||||||||||:||||||||||||||||
  Rat    11 ----GAGQDVGRSCILVSISGKNVMLDCGMHMGYNDDRRFPDFSYITQSGRLTDFLDCVIISHFH 71

Human   131 LDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVA 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    72 LDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVA 136

Human   196 VHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLL 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   137 VHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLL 201

Human   261 ITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPI 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   202 ITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPI 266

Human   326 YFSTGLTEKANHYYKLFIPWTNQKIRKTFVQRNMFEFKHIKAFDRAFADNPGPMVVFATPGMLHA 390
            ||||||||||||||||||.||||||||||||||||||||||||||.|||||||||||||||||||
  Rat   267 YFSTGLTEKANHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRTFADNPGPMVVFATPGMLHA 331

Human   391 GQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQVLEVKMQVEYMSFSAHADA 455
            ||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||
  Rat   332 GQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQMLEVKMQVEYMSFSAHADA 396

Human   456 KGIMQLVGQAEPESVLLVHGEAKKMEFLKQKIEQELRVNCYMPANGETVTLPTSPSIPVGISLGL 520
            ||||||||||||||||||||||||||||:||||||.||:||||||||||||||||||||||||||
  Rat   397 KGIMQLVGQAEPESVLLVHGEAKKMEFLRQKIEQEFRVSCYMPANGETVTLPTSPSIPVGISLGL 461

Human   521 LKREMAQ---------------------------GLLPEAKKPRLLHGTLIMKDSNFRLVSSEQA 558
            |||||.|                           ||||||||||||||||||||:||||||||||
  Rat   462 LKREMVQGMKGRLGHGSRGQVTGGWVDCIIPFFTGLLPEAKKPRLLHGTLIMKDNNFRLVSSEQA 526

Human   559 LKELGLAEHQLRFTCRVHLHDTRKEQETALRVYSHLKSVLKDHCVQHLPDGSVTVESVLLQAAAP 623
            |||||||||||||||||||.||||||||||||||||||.||||||||||||||||||:|:||||.
  Rat   527 LKELGLAEHQLRFTCRVHLQDTRKEQETALRVYSHLKSTLKDHCVQHLPDGSVTVESILIQAAAH 591

Human   624 SEDPGTKVLLVSWTYQ 639
            ||||||||||||||||
  Rat   592 SEDPGTKVLLVSWTYQ 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INTS11	XP_011539949.1	COG1782	69..506	CDD:441388	426/436 (98%)
		INTS11-like_MBL-fold	70..264	CDD:293849	190/193 (98%)
Ints11	XP_006239611.1	COG1782	5..447	CDD:441388	432/501 (86%)
		INTS11-like_MBL-fold	7..205	CDD:293849	194/257 (75%)