Protein Alignment INTS11 and ints11

DIOPT Version :10

• Sequence 1: XP_011539949.1
• Gene: INTS11 / 54973
• HGNCID: 26052
• Length: 660
• Species: Homo sapiens
• Sequence 2: XP_031761459.1
• Gene: ints11 / 100379959
• XenbaseID: XB-GENE-974122
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 660
• Identity: 537/660 - (81%)
• Similarity: 569/660 - (86%)
• Gaps: 60/660 - (9%)

Human     1 MPEIRVTPLGACPVLSWNLVLPPGRGSRAPSSTDTRTGFHVLPHGPLGCGPVILMCGAGFGHFEW 65
            ||||:||||
 Frog     1 MPEIKVTPL-------------------------------------------------------- 9

Human    66 LAGGGAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHFH 130
                |||||||||||||||.|||||||||||||:|||||||||||||||||||:|||||||||||
 Frog    10 ----GAGQDVGRSCILVSIGGKNVMLDCGMHMGYNDDRRFPDFSYITQNGRLTEFLDCVIISHFH 70

Human   131 LDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVA 195
            |||||||||.||||||||||||||||:|||||||||||||.||||||.|||||||||||||||||
 Frog    71 LDHCGALPYMSEMVGYDGPIYMTHPTKAICPILLEDYRKITVDKKGETNFFTSQMIKDCMKKVVA 135

Human   196 VHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLL 260
            |:||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||
 Frog   136 VNLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPDLL 200

Human   261 ITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPI 325
            |:||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||.||
 Frog   201 ISESTYATTIRDSKRCRERDFLKKVHETVEKGGKVLIPVFALGRAQELCILLETFWERMNLKAPI 265

Human   326 YFSTGLTEKANHYYKLFIPWTNQKIRKTFVQRNMFEFKHIKAFDRAFADNPGPMVVFATPGMLHA 390
            ||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||
 Frog   266 YFSTGLTEKANHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRAFADNPGPMVVFATPGMLHA 330

Human   391 GQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQVLEVKMQVEYMSFSAHADA 455
            |||||||||||||:||||||||||||||||||||||||||||||||.||||||||||||||||||
 Frog   331 GQSLQIFRKWAGNDKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQTLEVKMQVEYMSFSAHADA 395

Human   456 KGIMQLVGQAEPESVLLVHGEAKKMEFLKQKIEQELRVNCYMPANGETVTLPTSPSIPVGISLGL 520
            ||||||:.||||.:|||||||||||||||.|||||.|:||.||.||||.|:.|:|:|||.|||||
 Frog   396 KGIMQLIRQAEPRNVLLVHGEAKKMEFLKLKIEQEFRINCAMPLNGETATITTNPNIPVDISLGL 460

Human   521 LKREMAQGLLPEAKKPRLLHGTLIMKDSNFRLVSSEQALKELGLAEHQLRFTCRVHLHDTRKEQE 585
            ||:|.:.||:|:.|||||:||||||||::|||||.||||||:||.|||||||||:|:.||.||||
 Frog   461 LKKESSLGLVPDCKKPRLMHGTLIMKDNSFRLVSPEQALKEIGLGEHQLRFTCRLHVQDTHKEQE 525

Human   586 TALRVYSHLKSVLKDHCVQHLPDGSVTVESVLLQAAAPSEDPGTKVLLVSWTYQDEELGSFLTSL 650
            |.||:|:||||||||:.||||||||:.|||:|||.:..||||||||||:||||||||||||||||
 Frog   526 TVLRIYNHLKSVLKDYSVQHLPDGSIMVESILLQVSTHSEDPGTKVLLISWTYQDEELGSFLTSL 590

Human   651 LKKGLPQAPS 660
            |||||||..|
 Frog   591 LKKGLPQGTS 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INTS11	XP_011539949.1	COG1782	69..506	CDD:441388	410/436 (94%)
		INTS11-like_MBL-fold	70..264	CDD:293849	183/193 (95%)
ints11	XP_031761459.1	YSH1	5..416	CDD:440849	390/470 (83%)
		INTS11-like_MBL-fold	6..204	CDD:293849	187/257 (73%)