DRSC/TRiP Functional Genomics Resources

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Protein Alignment PPM1B and alph

DIOPT Version :9

Sequence 1:XP_016859884.1 Gene:PPM1B / 5495 HGNCID:9276 Length:487 Species:Homo sapiens
Sequence 2:NP_651701.1 Gene:alph / 43481 FlyBaseID:FBgn0086361 Length:374 Species:Drosophila melanogaster


Alignment Length:387 Identity:200/387 - (51%)
Similarity:260/387 - (67%) Gaps:23/387 - (5%)


- Green bases have known domain annotations that are detailed below.


Human     1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGS 65
            ||.|||||||.|||..|.||.|.:|:|||||||.|||||:.|..|:...|.|||||||:|||||.
  Fly     1 MGGFLDKPKTAKHNDEGEGNKLLFGVSSMQGWRSEMEDAYYARAGLGDALPDWSFFAVFDGHAGC 65

Human    66 RVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDR- 129
            :|:.:|:.||||.|.:.|:|           :..::|| |||||||:|||.||...:.....:: 
  Fly    66 KVSEHCAKHLLESIISTEEF-----------IGGDHVK-GIRTGFLRIDEVMRELPEFTRESEKC 118

Human   130 SGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNG 194
            .|:|||...:....:|..|||||||||.|.|...|:||||||..|.|||||.||||||||:||||
  Fly   119 GGTTAVCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVMIKRVNG 183

Human   195 SLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVK 259
            :|||||||||||:|.|..||..|||||||||::...|.:.|||::|||||||||||||::|.::.
  Fly   184 TLAVSRALGDYDFKNVKEKGQCEQLVSPEPEIFCQSRQDSDEFLVLACDGIWDVMSNEDVCSFIH 248

Human   260 SRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEGTF 324
            ||:.|:.:|.::.|.||||||||||||||||:::.|..|||.::||::.:..|:|.:|       
  Fly   249 SRMRVTSNLVSIANQVVDTCLHKGSRDNMSIIIIAFPGAPKPTEEAIEAEHRLEKQIE------- 306

Human   325 FKKPTEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDG 386
             |...:.:|.|......||...::  :.::|..|||||||..|.:|||..:.:..|.|..:|
  Fly   307 -KITRDEIESSKITDYVDLLKCLQ--NRDDIEGLPPGGGLQSKYHVIERTFKQEFPDRPCEG 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PPM1BXP_016859884.1 None
alphNP_651701.1 PP2Cc 24..284 CDD:238083 155/271 (57%)
PP2C_C 278..352 CDD:285117 27/83 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 305 1.000 Domainoid score I1370
eggNOG 1 0.900 - - E1_COG0631
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H2027
Inparanoid 1 1.050 390 1.000 Inparanoid score I2009
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53745
OrthoDB 1 1.010 - - D262211at33208
OrthoFinder 1 1.000 - - FOG0000692
OrthoInspector 1 1.000 - - mtm8647
orthoMCL 1 0.900 - - OOG6_100270
Panther 1 1.100 - - O PTHR47992
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X444
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1413.840

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