Protein Alignment PPM1B and CG10417

DIOPT Version :9

• Sequence 1: XP_016859884.1
• Gene: PPM1B / 5495
• HGNCID: 9276
• Length: 487
• Species: Homo sapiens
• Sequence 2: NP_610169.1
• Gene: CG10417 / 35492
• FlyBaseID: FBgn0033021
• Length: 662
• Species: Drosophila melanogaster
• Alignment Length: 648
• Identity: 150/648 - (23%)
• Similarity: 211/648 - (32%)
• Gaps: 298/648 - (45%)

Human     1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGS 65
            |||:|..|||:|.:.......|..|.|||||||...||||.:::...:   :.|||||||||.|:
  Fly     1 MGAYLSHPKTDKTSTDQFNELLAVGASSMQGWRNSQEDAHNSILNFDN---NTSFFAVYDGHGGA 62

Human    66 RVANYCS---THLLEHITT---------------------------------------------- 81
            .||.||:   .|.|:::.|
  Fly    63 EVAQYCADKLPHFLKNLETYKNGQFEVALKEAFLGFDKTLLDPSIVSILKILAGEHNFVDAEADD 127

Human    82 ----------------------------------------NEDF----------RAA-------- 88
                                                    .|:|          |||
  Fly   128 YEEEDLAELQEESNLPLNEVLEKYKGLPQKKDLDLKSSDHKENFKMRSPYFRGRRAAALAAEATN 192

Human    89 -----------GKSGS----ALELSVENVKN-------------------------GIRTGFLKI 113
                       |.|.|    |..||.:.|.|                         ..:...||.
  Fly   193 KAVMDPSAKPDGSSTSAAAAAAALSADGVANSRNPSNVVNPMAGADSNTTTSINDLSTKNAALKD 257

Human   114 D----------------------------------------------------EYMRN------- 119
            |                                                    |:.||
  Fly   258 DSVNDQNEGSNGTDFKHTLVSSSNKKLFATGSNDMTELNQSSKNEFTNSSTSKEFERNINSSQDD 322

Human   120 -FSD------------------------------------------------LRN---------- 125
             |:|                                                :.|
  Fly   323 EFTDDDADYEENDNVKSPDTSSAESSDCTENDDDGDEDGNEDSDEEETDEDQMANDNFCANMIEE 387

Human   126 -GMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI 189
             |.| ||.|||..::..:.:|..|.||||.|:.|:||....:.||||.:..|..||..|||.|.:
  Fly   388 PGKD-SGCTAVVCLLQGRDLYVANAGDSRCVISRSGQAIEMSIDHKPEDDEEASRIIKAGGRVTL 451

Human   190 Q-RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEE 253
            . ||||.|.:||||||:.||........||::|..|::.:::...||||::|||||||:.||:||
  Fly   452 DGRVNGGLNLSRALGDHAYKTNVTLPAEEQMISALPDIKKLIITPEDEFMVLACDGIWNYMSSEE 516

Human   254 LCEYVKSRLEVSDDLENVCNWVVDTCLHKGSR------DNMSIVLVCFSN---------APKVSD 303
            :.|:|:.||:.:..|..:|..:.|.||...:.      |||:.|:|.|..         .|..::
  Fly   517 VVEFVRCRLKDNKKLSTICEELFDNCLAPNTMGDGTGCDNMTAVIVQFKKKLQELQSTIPPNQTE 581

Human   304 EAVKKDSE------LDKHLESRVEGTFFKKPTEIMEKSGEEGMPDLAHVMRILSAENIPNLPP 360
            :.:.|.||      .|:....|..........||:||:..:      .:...|..|||.:..|
  Fly   582 DKLLKTSENVSHSLNDQSASKRCASQNADADDEILEKNNSK------RLKTDLEQENIKDRTP 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPM1B	XP_016859884.1	None
CG10417	NP_610169.1	PP2Cc	18..>100	CDD:214625	30/84 (36%)
		PP2Cc	<374..564	CDD:238083	75/190 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D957254at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100270
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.720