DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rrad and Rgk1

DIOPT Version :9

Sequence 1:	NP_001016726.1	Gene:	rrad / 549480	XenbaseID:	XB-GENE-491671	Length:	303	Species:	Xenopus tropicalis
Sequence 2:	NP_725875.3	Gene:	Rgk1 / 14462605	FlyBaseID:	FBgn0264753	Length:	1379	Species:	Drosophila melanogaster

Alignment Length:	353	Identity:	101/353 - (28%)
Similarity:	151/353 - (42%)	Gaps:	85/353 - (24%)

- Green bases have known domain annotations that are detailed below.

Frog     3 LNRSDRFKSLEKRRGSMPFSMHQQLHRRSMPVDDKELHGKTPASQLSSLVRCPSYNPSDEHRESW 67
            :||.|..||...|..:            |:...:......|...|||:    |:   |...|.|.
  Fly  1060 VNRGDSLKSRRSRSNN------------SVASSNSSTEHLTTQQQLSA----PA---SVSARTSL 1105

Frog    68 ASDSSDSVISSGSDSEDHVYKVILLGEHGVGKSSLARIFGGVEDLH----DVEEAGNTYDRSIVV 128
            ||....|..:.|:..    |:|::||...||||||...|...|.||    .:::.......|:::
  Fly  1106 ASSRESSTSNPGNGP----YRVLMLGGPAVGKSSLVSQFMTSEYLHAYDTSIDDESGEKAVSVLL 1166

Frog   129 DGEEACLLVFDIWEQDDNHWLHNQCMKMGD--AYVIVYSVTDKASFEKASELRIQLRRARQSEDI 191
            .|||:.|:..|   ........::|:...|  .|.::||..|::||..|.::...|...:.....
  Fly  1167 SGEESELIFID---HGYTEMTPDECLTNYDPHGYCVIYSAADRSSFSVAEQVLQVLWTNQNIAQK 1228

Frog   192 PIILVGNKSDLVRSREVSVEEGRACAVVFDCKFIETSASLHHNVKDLFEGIVRQIRLRKDSKEDN 256
            .:|||.||:||.|||.|:.|||:|.|..:||||||||..::|||.:|..|::.||||:.::.|.:
  Fly  1229 AVILVSNKADLARSRLVTSEEGKAMATAYDCKFIETSVGINHNVDELLVGLLSQIRLKLENPEKS 1293

Frog   257 -----ARRMASSKR-----------------------------------------RESIGKKAKR 275
                 .|.:..|||                                         |.|...|.|.
  Fly  1294 RDLFRKRSIRKSKRRACSPLNAGCLNANTPLGPLGEAVATPPGSAQSSPRKYRGSRTSTSLKVKG 1358

Frog   276 FLGKIVAKNNKKMAFKQKSKSCHDLSVL 303
            .||::..:::       |||||.:|.||
  Fly  1359 LLGRVWTRDS-------KSKSCENLHVL 1379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rrad	NP_001016726.1	RGK	87..303	CDD:206715	80/267 (30%)
Rgk1	NP_725875.3	DUF2967	459..715	CDD:288079
		P-loop_NTPase	1121..1379	CDD:304359	80/267 (30%)
		small_GTPase	1121..1286	CDD:197466	62/167 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D301527at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5084
SonicParanoid	1	1.000	-	-		X743
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.040