Protein Alignment TRMT10C and TRM10

DIOPT Version :10

• Sequence 1: NP_060289.2
• Gene: TRMT10C / 54931
• HGNCID: 26022
• Length: 403
• Species: Homo sapiens
• Sequence 2: NP_014548.1
• Gene: TRM10 / 854060
• SGDID: S000005453
• Length: 293
• Species: Saccharomyces cerevisiae
• Alignment Length: 288
• Identity: 69/288 - (23%)
• Similarity: 129/288 - (44%)
• Gaps: 48/288 - (16%)

Human   108 VPEHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETTEED 172
            |||.:::::.|.:  |.....::...|| ..:.:|||.| ::.|..|..:|      .::..||.
Yeast    22 VPEGMSKKQWKKM--CKRQRWEENKAKY-NAERRVKKKR-LRHERSAKIQE------YIDRGEEV 76

Human   173 KQKNFLFLRLWDRNMDIAMGWKGAQAMQFGQPLVFDMAYENYMKRKELQNTVSQLLESEGWNRR- 236
            .|:.....|:            .......|..::.|.:::..|..||:.:..:|:..:...|||
Yeast    77 PQELIREPRI------------NVNQTDSGIEIILDCSFDELMNDKEIVSLSNQVTRAYSANRRA 129

Human   237 NVDPFHIYFCNLKIDGALHRELVKRYQ--------EKWDKLLLTSTEK-----SHVDLFPKDSII 288
            |      :|..:|: ....:.|.:|::        |.|:.......:|     .|:.   ||.|:
Yeast   130 N------HFAEIKV-APFDKRLKQRFETTLKNTNYENWNHFKFLPDDKIMFGDEHIS---KDKIV 184

Human   289 YLTADSPNVMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGNKNLTL 353
            |||||:...:........|::|..|||:......|.||:::.:.|..||:|:|:..| |.:.||.
Yeast   185 YLTADTEEKLEKLEPGMRYIVGGIVDKNRYKELCLKKAQKMGIPTRRLPIDEYINLE-GRRVLTT 248

Human   354 DQMIRILLCLKNNGNWQEALQFV-PKRK 380
            ..:::::|...::.||:.|.:.| |.||
Yeast   249 THVVQLMLKYFDDHNWKNAFESVLPPRK 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRMT10C	NP_060289.2	Trm10_MRRP1	203..380	CDD:349975	48/191 (25%)
TRM10	NP_014548.1	SPOUT_Trm10-like	97..271	CDD:349962	46/184 (25%)