Protein Alignment TMEM161A and emei

DIOPT Version :10

• Sequence 1: NP_060284.1
• Gene: TMEM161A / 54929
• HGNCID: 26020
• Length: 479
• Species: Homo sapiens
• Sequence 2: NP_648439.1
• Gene: emei / 39250
• FlyBaseID: FBgn0036133
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 493
• Identity: 177/493 - (35%)
• Similarity: 290/493 - (58%)
• Gaps: 19/493 - (3%)

Human     1 MAVLGVQLVVTLLTATLMHRLAPHCSFARWLLCNGSLFRYKHPSEEELRALAGKPR---PRGRKE 62
            |||||.|||:||:..:::.:|:||.|||:|:||...|:||.||:::|||:..|.|:   |:|.:.
  Fly     1 MAVLGAQLVITLVMVSVIQKLSPHYSFAKWILCRTGLYRYLHPTDDELRSRGGVPKEKPPKGGRN 65

Human    63 RWANGL--SEEKPLSVPRDAPFQLETCPLTTVDALVLRFFLEYQWFVDFAVYSGGVYLFTEAYYY 125
            :.|||.  :......:||....:|.|.|:...|.:.||:|.||||.:||:||:|.||:.:|.:::
  Fly    66 KQANGSGGAAGAQFHIPRSIEVELLTSPVLERDVVHLRYFTEYQWLLDFSVYTGIVYVVSELFHF 130

Human   126 MLGPAKETNIAVFWCLLTVTFSIKMFLTVTRLYFSAEEG-GERSVCLTFAFLFLLLAMLVQVVRE 189
            ......|.|:::.||||.:.|::|:..::|.|||.:||. ||||:.:....::||:||:|.:|.|
  Fly   131 YYPLRHEVNLSMVWCLLVIFFALKLLSSLTVLYFQSEESIGERSMVIVACLVYLLVAMVVLIVDE 195

Human   190 ETLELGLEPGLASMTQNLEPLLKKQGWDWALPVAKLAIRVGLAVVGSVLGAFLTFPGLRLAQTHR 254
            ..||.|||...||...:....|.:||...:.|.:|:.::..||:...:||:..||||||:|:.|.
  Fly   196 RILETGLEDAYASFNASASKFLTEQGLPSSGPASKIVVKFFLAMGCGLLGSLFTFPGLRMAKMHW 260

Human   255 DALTMSEDRPMLQFLLHTSFLSPLFILWLWTKPIARDFLHQPPFGETRFSLLSDSAFDSGRLWLL 319
            |:|.......:||.||:.||:.|..::.||.:||:||:|....|...:..||....|::.||.|:
  Fly   261 DSLKYCRGNRLLQVLLNLSFVLPFILVILWIRPISRDYLTVRVFQGMQQPLLKPHVFETLRLLLV 325

Human   320 VVLCLLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEAREIQQRVVRVYCYVTVVSLQYLTPLIL 384
            :.:.::|.|:...:||:||.||..::..||:|||||...|.:|::..::.|:.||:||:..||||
  Fly   326 IFVVVVRFALMPIYLQSYLNLAHDKIMDLRKEAGRITNVEFKQKISSIFYYLCVVTLQFAAPLIL 390

Human   385 TLNCTLLLKTLGGYSW-GLGPAPLLSPDPSSAS-------AAPIGSGEDEVQQTAARIAGALGGL 441
            .|..||:.|:|||:|| |:....::.....:||       |...|.|:..:.::|..:..:...|
  Fly   391 CLYLTLMYKSLGGFSWSGIFRESVVLQHECAASETEGAGVAVSQGDGDFNIIESAQSLQASFSSL 455

Human   442 ----LTPLFLRGVLAYLIWWTAACQLLASLFGLYFHQH 475
                .|.:: :|.|.:..||:.......|..|:.:..:
  Fly   456 KNVFSTEVY-KGFLGFATWWSYFTLFATSSLGIVYQSY 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMEM161A	NP_060284.1	Tmemb_161AB	2..476	CDD:463037	176/492 (36%)
emei	NP_648439.1	Tmemb_161AB	2..493	CDD:463037	176/492 (36%)