DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UBE2R2 and vih

DIOPT Version :9

Sequence 1:	NP_060281.2	Gene:	UBE2R2 / 54926	HGNCID:	19907	Length:	238	Species:	Homo sapiens
Sequence 2:	NP_648582.1	Gene:	vih / 44118	FlyBaseID:	FBgn0264848	Length:	178	Species:	Drosophila melanogaster

Alignment Length:	156	Identity:	56/156 - (35%)
Similarity:	81/156 - (51%)	Gaps:	24/156 - (15%)

- Green bases have known domain annotations that are detailed below.

Human    11 KALMLELKSL---QEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSP 72
            |.|..||.:|   .|..:..|    .|..:::.|...|.||.||:|.|..::..:.||..|||:.
  Fly    35 KRLHKELMNLMMANERGISAF----PDGENIFKWVGTIAGPRNTVYSGQTYRLSLDFPNSYPYAA 95

Human    73 PTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTF 137
            |..:|||..:|||:...|.:|:.||             .::|:...:|||||||:.|||.|||..
  Fly    96 PVVKFLTSCFHPNVDLQGAICLDIL-------------KDKWSALYDVRTILLSIQSLLGEPNNE 147

Human   138 SPANVDASVMFRKWRDSKGKDKEYAE 163
            ||.|..|::|   |.|.| :.|:|.:
  Fly   148 SPLNAQAAMM---WNDQK-EYKKYLD 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UBE2R2	NP_060281.2	UBCc	11..169	CDD:238117	56/156 (36%)
UBE2R2	NP_060281.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..238
vih	NP_648582.1	COG5078	31..166	CDD:227410	54/151 (36%)
vih	NP_648582.1	UQ_con	36..172	CDD:278603	55/155 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910