Protein Alignment UBE2R2 and CG7656

DIOPT Version :10

• Sequence 1: NP_060281.2
• Gene: UBE2R2 / 54926
• HGNCID: 19907
• Length: 238
• Species: Homo sapiens
• Sequence 2: NP_648783.4
• Gene: CG7656 / 39691
• FlyBaseID: FBgn0036516
• Length: 319
• Species: Drosophila melanogaster
• Alignment Length: 239
• Identity: 159/239 - (66%)
• Similarity: 197/239 - (82%)
• Gaps: 14/239 - (5%)

Human     7 TSSQKALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYS 71
            :|:.:||.:|.||||||||||||:.|:::.:|:.|||||||||:|||:|||||||:|||.|||||
  Fly    39 SSAVRALAMEYKSLQEEPVEGFRVKLINDDNLFEWEVAIFGPPDTLYQGGYFKAHMKFPHDYPYS 103

Human    72 PPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNT 136
            ||:.|||||:||||:|||||:||||||||||||||||||.|||||||||||||||||||||||||
  Fly   104 PPSIRFLTKVWHPNVYENGDLCISILHPPVDDPQSGELPCERWNPTQNVRTILLSVISLLNEPNT 168

Human   137 FSPANVDASVMFRKWRDSKGKDKEYAEIIRKQVSATKAEAEKDGVKVPTTLAEYCIK-TKVPSND 200
            |||||||||||:|:||||:|||.||..|||||..|..|||:::|:.||.||.:||:| |:.|:.:
  Fly   169 FSPANVDASVMYRRWRDSQGKDNEYPNIIRKQALAANAEAKREGIVVPMTLEDYCLKPTRKPTTE 233

Human   201 NSSDL-LYDDLY----------DDDIDDEDEEEEDADCYDDDDS 233
            :..|. .|||.:          |||.|::|:::||.|  :|:||
  Fly   234 SGLDANFYDDDFDLETEDDLPSDDDFDEDDDDDEDED--EDEDS 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBE2R2	NP_060281.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..238		17/51 (33%)
		UBCc_UBE2R	11..180	CDD:467423	133/168 (79%)
		Important for ubiquitin transfer. /evidence=ECO:0000269|PubMed:38326650	98..113		13/14 (93%)
CG7656	NP_648783.4	UBCc_UBE2R	43..212	CDD:467423	133/168 (79%)