DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UBE2R2 and CG40045

DIOPT Version :9

Sequence 1:	NP_060281.2	Gene:	UBE2R2 / 54926	HGNCID:	19907	Length:	238	Species:	Homo sapiens
Sequence 2:	NP_001036640.1	Gene:	CG40045 / 3355079	FlyBaseID:	FBgn0058045	Length:	168	Species:	Drosophila melanogaster

Alignment Length:	175	Identity:	89/175 - (50%)
Similarity:	117/175 - (66%)	Gaps:	11/175 - (6%)

- Green bases have known domain annotations that are detailed below.

Human     6 MTSSQKALML--ELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDY 68
            |:..|.:|:|  :|..|.:.|||||...|:||:|::.|||.|.|||:||||||:||||:.||.:|
  Fly     1 MSELQSSLLLKKQLAELNKNPVEGFSAGLIDENDIFRWEVLIIGPPDTLYEGGFFKAHLYFPKEY 65

Human    69 PYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNE 133
            |..||..:|:|::|||||.:||||||||||.|.||....|..||||.|...|.|||:||||:|.:
  Fly    66 PLRPPRMKFVTEIWHPNIEKNGDVCISILHEPGDDKWGYEKASERWLPVHTVETILISVISMLAD 130

Human   134 PNTFSPANVDASVMFRKWRDSKGKDKEYAEIIRKQVSATKAEAEK 178
            ||..|||||||:   ::||:|      |.:..||.....:...|:
  Fly   131 PNDESPANVDAA---KEWRES------YTDFKRKVARCVRKSQEE 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UBE2R2	NP_060281.2	UBCc	11..169	CDD:238117	86/159 (54%)
UBE2R2	NP_060281.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..238
CG40045	NP_001036640.1	UQ_con	10..160	CDD:395127	85/158 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0425
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810