Protein Alignment DNAAF5 and PRS3

DIOPT Version :10

• Sequence 1: NP_060272.3
• Gene: DNAAF5 / 54919
• HGNCID: 26013
• Length: 855
• Species: Homo sapiens
• Sequence 2: NP_011852.1
• Gene: PRS3 / 856375
• SGDID: S000001003
• Length: 320
• Species: Saccharomyces cerevisiae
• Alignment Length: 219
• Identity: 37/219 - (16%)
• Similarity: 72/219 - (32%)
• Gaps: 65/219 - (29%)

Human   657 ILAPNLQWHAGRTAAAIRTAAVSCLWALTSSEVLS----------AEQIRDVQETLMPQVLTTLE 711
            :|||::  |.|......:...:.    ||||::..          .|.:||....::.|:.:.:.
Yeast     8 LLAPDV--HRGLAELVAKRLGLQ----LTSSKLKRDPTGEVSFSIGESVRDQDIFIITQIGSGVV 66

Human   712 EDSKMTRLISCRIINTFLKTSGGMTDPEKLIRIYPELLKRLDDVSNDVRMAAASTLVTWLQCVKG 776
            .|..:..||   :||. .||:..    .::..|.|.......|..:..|....:.|:..:....|
Yeast    67 NDRVLELLI---MINA-SKTASA----RRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAG 123

Human   777 -----------ANAKSYYQSSVQYLYRELLVHLDDPERAIQDAILEVLKEGSGLFPDLLVRETE- 829
                       :..:.::...|..||.|             .:::..:||.......:::....
Yeast   124 CDHVITMDLHASQIQGFFDVPVDNLYAE-------------PSVVRYIKENVNYMDSIIISPDAG 175

Human   830 ----------------AVIHKHRS 837
                            |:|||.|:
Yeast   176 GAKRAATLADRLDLNFALIHKERA 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAAF5	NP_060272.3	HEAT 1	71..109
		HEAT	165..306	CDD:441023
		HEAT repeat	166..192	CDD:293787
		HEAT 2	202..240
		HEAT 3	241..278
		HEAT repeat	246..274	CDD:293787
		HEAT 4	280..318
		HEAT repeat	285..315	CDD:293787
		HEAT 5	354..376
		HEAT repeat	359..385	CDD:293787
		HEAT 6	377..414
		HEAT 7	599..638
		HEAT 8	696..734		10/37 (27%)
		HEAT repeat	701..731	CDD:293787	6/29 (21%)
		HEAT 9	738..776		5/37 (14%)
		HEAT repeat	740..772	CDD:293787	5/31 (16%)
		HEAT repeat	783..813	CDD:293787	4/29 (14%)
		HEAT 10	784..822		6/37 (16%)
PRS3	NP_011852.1	PrsA	4..315	CDD:440230	37/219 (17%)