Protein Alignment RNF43 and rnf13

DIOPT Version :9

• Sequence 1: XP_011523257.1
• Gene: RNF43 / 54894
• HGNCID: 18505
• Length: 869
• Species: Homo sapiens
• Sequence 2: NP_957338.1
• Gene: rnf13 / 793981
• ZFINID: ZDB-GENE-040426-772
• Length: 377
• Species: Danio rerio
• Alignment Length: 276
• Identity: 71/276 - (25%)
• Similarity: 121/276 - (43%)
• Gaps: 66/276 - (23%)

Human    77 PAEGK---LMQSHPLYLCNASDD----DNLEPGFISIVKLESPRRAPRPCLSLASKARMAGERG- 133
            |:||.   |:.:.|...|...:.    :||...||.:::        |...:...|...|.:.|
Zfish    60 PSEGLKGFLIGARPENACVPIEPPPQRENLSSAFIVLIR--------RFDCNFDIKVLHAQKAGY 116

Human   134 ASAVLFDITED---RAAAEQLQQPLGLTWPVVLIWGNDAEKLME-FVYKNQKAHVRIELKEPPAW 194
            .:|::.::..|   ...:|.|.....:..|.|.|....|..|.| ::|: :..||.:       .
Zfish   117 KAAIVHNVDSDDLISMGSEDLDILKQIDIPSVFIGEEAANSLKEDYIYE-KGGHVIL-------M 173

Human   195 PDYDVWI------LMTVVGTIFVIILASVL------RIRCRPRHSRPDPLQQRTAWAISQLATRR 247
            ||:.:.:      .:.:||...::|:..::      |.|.|....|.|.|:        :|...:
Zfish   174 PDFSLPLEYYLIPFLIIVGICLILIVVFMITKFVQDRHRARRSRLRKDQLK--------KLPIHK 230

Human   248 YQASCRQARGEWPDSGSSCSSAPVCAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQ-HRTCPL 311
            ::      :|:         |..||||||:|:.||:.|||:.|.|.:|..||||||.: .:|||:
Zfish   231 FK------KGD---------SYDVCAICLDEYEEGERLRVLPCSHAYHCKCVDPWLTKTKKTCPV 280

Human   312 CMFNI--TEGDSFSQS 325
            |...:  ::|||.|.|
Zfish   281 CKQKVVPSDGDSESDS 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNF43	XP_011523257.1	Peptidases_S8_S53	<87..186	CDD:299169	23/107 (21%)
		zf-RING_2	270..312	CDD:290367	24/42 (57%)
rnf13	NP_957338.1	PA_C_RZF_like	23..180	CDD:239038	29/135 (21%)
		zf-RING_2	238..282	CDD:290367	24/43 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920