Protein Alignment RNF43 and gol

DIOPT Version :9

• Sequence 1: XP_011523257.1
• Gene: RNF43 / 54894
• HGNCID: 18505
• Length: 869
• Species: Homo sapiens
• Sequence 2: NP_001163300.1
• Gene: gol / 38006
• FlyBaseID: FBgn0004919
• Length: 601
• Species: Drosophila melanogaster
• Alignment Length: 350
• Identity: 86/350 - (24%)
• Similarity: 137/350 - (39%)
• Gaps: 85/350 - (24%)

Human   125 KARMAGE-RGASAVLFDITEDRAAAEQLQQPLGLTW------PVVLIWGNDAEKLMEFVYKNQKA 182
            |.::.|: |..:||:        ..:.:.|.|.||.      .:.:|.|....:.:..:.:....
  Fly   180 KMQIKGKTRNIAAVI--------TYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVL 236

Human   183 HVRIELKEPPAWPDYDVWILMTVVGTIFVIILASVLRIRCRPRHSRPDPLQQRTAWAISQLATRR 247
            .|.|         .:.|.:::::|..||..|.        |.|:.:....|.|...::::.|..:
  Fly   237 FVSI---------SFIVLMIISLVWLIFYYIQ--------RFRYMQAKDQQSRNLCSVTKKAIMK 284

Human   248 YQASCRQARGEWPDSGSSCSSAPVCAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLC 312
            ......:...| .|..|.|     ||||:|.:.....:|::.|.||||:||:||||.:|||||:|
  Fly   285 IPTKTGKFSDE-KDLDSDC-----CAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMC 343

Human   313 MFNITE--GDSFSQSLGPSRS---YQ-EPGRRLHLIRQHPGHAHYHLPAAYLLGPSRSAVARPPR 371
            ..::.:  |..|   ||...|   || :|.:.|.|:......|.        |..||..|...||
  Fly   344 KLDVLKFYGYVF---LGSEESILEYQPDPPQGLALVEARDESAD--------LNRSRDFVVDFPR 397

Human   372 PGPFLPSQEPGMGPRHHRFPRAAHPRAPG-------------------EQQRLAGAQHPYAQGWG 417
              .|:......:|.|...||.....|:..                   |||.|...::...|...
  Fly   398 --VFVLDSGCVVGAREMLFPCRIPERSQSSLSLRQARDWVSLMSNKLEEQQGLRSMRNDEMQQQL 460

Human   418 LSHLQSTSQHPAACPVPLRRARPPD 442
            ||..:| ::|        ||:|..|
  Fly   461 LSARES-ARH--------RRSRSAD 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNF43	XP_011523257.1	Peptidases_S8_S53	<87..186	CDD:299169	12/67 (18%)
		zf-RING_2	270..312	CDD:290367	22/41 (54%)
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	9/44 (20%)
		UPF0233	226..>258	CDD:299753	6/40 (15%)
		zf-RING_2	301..344	CDD:290367	23/47 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920