DRSC/TRiP Functional Genomics Resources

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Protein Alignment NSUN2 and Nsun5

DIOPT Version :10

Sequence 1:NP_060225.4 Gene:NSUN2 / 54888 HGNCID:25994 Length:767 Species:Homo sapiens
Sequence 2:NP_650787.1 Gene:Nsun5 / 7354421 FlyBaseID:FBgn0259704 Length:433 Species:Drosophila melanogaster


Alignment Length:302 Identity:75/302 - (24%)
Similarity:116/302 - (38%) Gaps:59/302 - (19%)


- Green bases have known domain annotations that are detailed below.


Human    39 PEIVKENKLFEHYYQELKIVPEGEWGQFMDALREPLPATLRITGYKSHAKEILHCLKNKYFKELE 103
            |..|:.|.......:.|..:.:.:|      .|:.|||.   ..|......|....:|::   :.
  Fly   128 PRYVRINTNLYSLAEALDYLHKSDW------RRKELPAD---ASYADFLTAIKSLAENEF---MT 180

Human   104 DLEVDGQKVEVPQPLSWYPEELAWHTNLSRKILRKSPHLEKFHQFLVSETESGNISRQEAVSMIP 168
            ||.|:|..:        :|.:  |.....|..|   .|.::|            |.:.:|..:..
  Fly   181 DLHVEGVLI--------FPAK--WSNYWVRHPL---VHSKRF------------ILQNKATCLAA 220

Human   169 PLLLNVRPH-HKILDMCAAPGSKTTQLIEMLHADMNVPFPEGFVIANDVDNKRCYLLVHQAKRLS 232
            .||  ..|. ..:||||||||.||..:       .||...:|.:.:.:.|:.|...|....|...
  Fly   221 ELL--APPSGATVLDMCAAPGMKTVHI-------CNVMQNKGCIYSVEQDHVRYNTLCEITKDAG 276

Human   233 SPCIMVVNHDASSI-PRLQIDVDGRKEILFYDRILCDVPCSGDGTMRKNIDVWKKWTTLNSLQ-L 295
            ...:..:..||.:: |....||         :.||.|..|||.| |:..:.|..:......|| |
  Fly   277 CDIVKPILGDALNLTPERFPDV---------EYILVDPSCSGSG-MQNRMTVCDEPKEDKRLQKL 331

Human   296 HGLQLRIATRGAEQLAEGGRMVYSTCSLNPIEDEAVIASLLE 337
            .|||::|.:..........|:.|.||||...|:|.|:...|:
  Fly   332 QGLQIKILSHAMGAFPNVKRIAYCTCSLWKEENEQVVQRCLQ 373

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NSUN2NP_060225.4 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..36
RsmB <59..431 CDD:439914 71/282 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 436..481
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 719..767
Nsun5NP_650787.1 RsmB <177..428 CDD:439914 63/244 (26%)
Blue background indicates that the domain is not in the aligned region.

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