DRSC/TRiP Functional Genomics Resources

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Protein Alignment NSUN2 and CG11109

DIOPT Version :10

Sequence 1:NP_060225.4 Gene:NSUN2 / 54888 HGNCID:25994 Length:767 Species:Homo sapiens
Sequence 2:NP_730761.1 Gene:CG11109 / 40507 FlyBaseID:FBgn0037200 Length:439 Species:Drosophila melanogaster


Alignment Length:386 Identity:98/386 - (25%)
Similarity:150/386 - (38%) Gaps:111/386 - (28%)


- Green bases have known domain annotations that are detailed below.


Human    67 MDALREPLPATLRIT-GYKSHAKEILHCLKN------------KYFK-----ELEDLEVD----- 108
            :|..|:.|...|.|. |.||..   ::||.|            :..|     ||:::.||     
  Fly    51 VDDFRKKLEEKLAIRYGVKSPR---IYCLPNLPEMLCIDPLDSQLTKAVADSELKEVVVDTNCGA 112

Human   109 ----GQKVEVPQPLSWYP----EELA-WHTNLSRKILR------KSPH----------LEKFHQF 148
                |..:..|..|:...    |||. .:.:|..|..|      :||:          ::::..|
  Fly   113 ALLRGAHIYAPGVLAMESNTEREELVNVYADLDGKCKRGTVKRYESPNKVFLGTGKVLMQRYQLF 177

Human   149 LVSETESGNIS--RQEAVSMIPPL--------------------LLNVRPHHKILDMCAAPGSKT 191
            ..:|..:..::  .|..||.:|.|                    :|:.:|..:|||||||||:||
  Fly   178 NNAEKPASGVAVEMQSNVSGVPTLGDLSSEDGLLQNLPSIVCVRVLDPQPGERILDMCAAPGNKT 242

Human   192 TQLIEMLHADMNVPFPEGFVIANDVDNKRCYLLVHQAKRLSSPCIMVVNH------DASSIPRLQ 250
            :.:.|::.       ..|.|:|.|....|...::.:.....|....|.|.      ||.|.|..:
  Fly   243 SHIAELMG-------DRGSVVALDNSASRVRSMLPKLGHYKSITAHVFNSTEAVAADAPSAPVGE 300

Human   251 IDVDGRKEILF---------YDRILCDVPCSGDGTMRKNIDVWKKWTTLNSLQLHGLQLRIATRG 306
                      |         :||||.|.||||.|. |..:....|...:.|...| :|.|:..:.
  Fly   301 ----------FTGPPFPCESFDRILLDAPCSGLGN-RPQLSCSIKQVKVLSSYPH-IQRRLFEQA 353

Human   307 AEQLAEGGRMVYSTCSLNPIEDEAVIASLLEKSEGALELADVSNEL--PGLKWMPGITQWK 365
            .:.:..||.:|||||::...|.|.::|..|.|.. .|.|.|.:...  |||. :||....|
  Fly   354 VQLVRPGGILVYSTCTVTEDECECLVAWALRKFV-ELRLTDATPRWGGPGLP-LPGFEACK 412

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NSUN2NP_060225.4 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..36
RsmB <59..431 CDD:439914 98/386 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 436..481
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 719..767
CG11109NP_730761.1 PUA_NSun6-like 102..195 CDD:409292 16/92 (17%)
RsmB <207..439 CDD:439914 64/227 (28%)
Blue background indicates that the domain is not in the aligned region.

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