Protein Alignment NSUN2 and Nsun2

DIOPT Version :10

• Sequence 1: NP_060225.4
• Gene: NSUN2 / 54888
• HGNCID: 25994
• Length: 767
• Species: Homo sapiens
• Sequence 2: NP_001101873.1
• Gene: Nsun2 / 361191
• RGDID: 1311954
• Length: 782
• Species: Rattus norvegicus
• Alignment Length: 767
• Identity: 659/767 - (85%)
• Similarity: 693/767 - (90%)
• Gaps: 10/767 - (1%)

Human     1 MGRRSRGRRLQQQQRPEDAEDGAEGGGKRGEAGWEGGYPEIVKENKLFEHYYQELKIVPEGEWGQ 65
            ||||:||||.||..:||..|||::|..|||:.|||||||||:|||||||||||||||||||||.|
  Rat    26 MGRRARGRRFQQPPQPEGEEDGSDGSRKRGQEGWEGGYPEIIKENKLFEHYYQELKIVPEGEWDQ 90

Human    66 FMDALREPLPATLRITGYKSHAKEILHCLKNKYFKELEDLEVDGQKVEVPQPLSWYPEELAWHTN 130
            ||.:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    91 FMGSLREPLPATLRITGYKSHAKEILHCLKNKYFKELEDLEVDGQKVEVPQPLSWYPEELAWHTN 155

Human   131 LSRKILRKSPHLEKFHQFLVSETESGNISRQEAVSMIPPLLLNVRPHHKILDMCAAPGSKTTQLI 195
            ||||||||||.|.|||||||||||||||||||||||||||||||.||||||||||||||||||||
  Rat   156 LSRKILRKSPLLAKFHQFLVSETESGNISRQEAVSMIPPLLLNVEPHHKILDMCAAPGSKTTQLI 220

Human   196 EMLHADMNVPFPEGFVIANDVDNKRCYLLVHQAKRLSSPCIMVVNHDASSIPRLQIDVDGRKEIL 260
            |||||||:||||||||||||||||||||||||||||||||||||||||||||||.:|||||||||
  Rat   221 EMLHADMSVPFPEGFVIANDVDNKRCYLLVHQAKRLSSPCIMVVNHDASSIPRLTVDVDGRKEIL 285

Human   261 FYDRILCDVPCSGDGTMRKNIDVWKKWTTLNSLQLHGLQLRIATRGAEQLAEGGRMVYSTCSLNP 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   286 FYDRILCDVPCSGDGTMRKNIDVWKKWTTLNSLQLHGLQLRIATRGAEQLAEGGRMVYSTCSLNP 350

Human   326 IEDEAVIASLLEKSEGALELADVSNELPGLKWMPGITQWKVMTKDGQWFTDWDAVPHSRHTQIRP 390
            :|||||||:|||||||||||||||.||||||||||::||||||:|||||.||..||..|||||||
  Rat   351 VEDEAVIAALLEKSEGALELADVSAELPGLKWMPGVSQWKVMTRDGQWFADWQEVPQGRHTQIRP 415

Human   391 TMFPPKDPEKLQAMHLERCLRILPHHQNTGGFFVAVLVKKSSMPWNKRQPKLQGKSAETRESTQL 455
            |||||||.:|||||||||||||||||||||||||||||||:.|||||||||:|.|||:.|:....
  Rat   416 TMFPPKDLDKLQAMHLERCLRILPHHQNTGGFFVAVLVKKAPMPWNKRQPKVQSKSAQARDPKAS 480

Human   456 SPADLTEGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSKKDGVCGPPPSKKMKLFGFKEDPF 520
            :....|:|.|:|.|:|||...||.||:|.|..||:.|:| .||||||||||||||||||||||||
  Rat   481 NTVAATKGNPSDQSELESQMITGAGDSEAAQTTENTESN-EKKDGVCGPPPSKKMKLFGFKEDPF 544

Human   521 VFIPEDDPLFPPIEKFYALDPSFPRMNLLTRTTEGKKRQLYMVSKELRNVLLNNSEKMKVINTGI 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   545 VFIPEDDPLFPPIEKFYALDPSFPRMNLLTRTTEGKKRQLYMVSKELRNVLLNNSEKMKVINTGI 609

Human   586 KVWCRNNSGEEFDCAFRLAQEGIYTLYPFINSRIITVSMEDVKILLTQENPFFRKLSSETYSQAK 650
            |||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||.|||.|
  Rat   610 KVWCRNNSGEEFDCAFRLAQEGIYTLYPFINSRIITVSMEDVKTLLTQENPFFRKLSSEAYSQVK 674

Human   651 DLAKGSIVLKYEPDSANPDALQCPIVLCGWRGKASIRTFVPKNERLHYLRMMGLEVLGEKKKEGV 715
            ||.|||:||||||||||||.|:|||||||||||||||||||||||||||||||||||||||||||
  Rat   675 DLTKGSVVLKYEPDSANPDTLRCPIVLCGWRGKASIRTFVPKNERLHYLRMMGLEVLGEKKKEGV 739

Human   716 ILTNESAASTGQPDNDVTEGQRAGEPNSPDAEEANSPDVTAGCDPAGVHPPR 767
            ||||||.||..||:.:..: |.|.:|.:||:        ..||||....|.|
  Rat   740 ILTNESVASPEQPEEEDAK-QTAQDPCNPDS--------VPGCDPGAAEPSR 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NSUN2	NP_060225.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		21/34 (62%)
		RsmB	<59..431	CDD:439914	349/371 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	436..481		21/44 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	719..767		17/47 (36%)
Nsun2	NP_001101873.1	RsmB	<84..456	CDD:439914	349/371 (94%)