DRSC/TRiP Functional Genomics Resources

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Protein Alignment NSUN2 and l(2)10685

DIOPT Version :10

Sequence 1:NP_060225.4 Gene:NSUN2 / 54888 HGNCID:25994 Length:767 Species:Homo sapiens
Sequence 2:NP_608573.1 Gene:l(2)10685 / 33293 FlyBaseID:FBgn0283525 Length:503 Species:Drosophila melanogaster


Alignment Length:440 Identity:104/440 - (23%)
Similarity:174/440 - (39%) Gaps:136/440 - (30%)


- Green bases have known domain annotations that are detailed below.


Human    11 QQQQR------PEDAEDGA--------------EGGGKRGEAGWEGGYPEIVKEN-KLFEHYYQE 54
            :||:|      |...|||:              |...::....::....:.::|: ||.||    
  Fly   127 KQQEREVASIYPSSPEDGSSAPLPLELKFDNVEEDQPEQVNNPFKQSLTKALEEDVKLDEH---- 187

Human    55 LKIVPEGEWGQFMDALREPLPATLRITGYKSHAKEILHCLKNKYFKELEDLEVDGQKVEVPQPLS 119
             ::| :.::|  ...|.|.:||. .|.|.:....|..|   .||::...|..:   .:| |:|..
  Fly   188 -RLV-DPQFG--TGGLYEYMPAH-SIKGMEDWVAESEH---YKYYQTSADFPL---AIE-PEPSF 240

Human   120 WYPEELAWHTNLSRKILRKSPHLEKFHQFLVSETESGNIS----------------RQEAVSMIP 168
            .|||.|:.:|                       .|.||.|                ..:..|.:|
  Fly   241 HYPEHLSLYT-----------------------YEMGNCSDFKGPKKCMTGVLSHFMMDGASTLP 282

Human   169 PLLLNVRPHHKILDMCAAPGSKTTQLIEMLHADMNVPFPEGFVIANDVDNKRC---------YLL 224
            ||.|.|:|..::||.||:||.|:..:::.||.|        .::.||:...|.         ||.
  Fly   283 PLFLQVKPGERVLDACASPGGKSLLMLQTLHLD--------HLVCNDIQESRLNKLRKVMQEYLF 339

Human   225 VHQAKRLSSPCIMVVNHDASSIPRLQIDVDGRKEILFYDRILCDVPCSGDGTMRKNID--VWKKW 287
            .:: :|.:...:::...||.::.:.:          .:|:||.||||:.|..:....|  ::|..
  Fly   340 DYK-ERWAGKRLILSQSDARNLDQYE----------QFDKILVDVPCTTDRHVLNEQDNNIFKPT 393

Human   288 TTLNSLQLHGLQLRIATRGAEQLAEGGRMVYSTCSLNPIEDEAVIASLLEKSEGALELADVSNEL 352
            .....|::..||..|.......|..||.:|||||||:||:::.|:...|:               
  Fly   394 RIKERLRIPELQAGILANCLRLLRPGGSLVYSTCSLSPIQNDGVVHMALQ--------------- 443

Human   353 PGLKWMPGITQWKVMTKDGQWFTDWDAVPHSRHTQIRPTMFPPKDPEKLQ 402
                        ||.|:.|...|..|.   ||||.:...:|..:.|:.|:
  Fly   444 ------------KVFTEYGITTTIKDL---SRHTALFSDVFKFEHPKGLK 478

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NSUN2NP_060225.4 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..36 8/44 (18%)
RsmB <59..431 CDD:439914 90/371 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 436..481
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 719..767
l(2)10685NP_608573.1 RsmB <276..444 CDD:439914 53/213 (25%)
Blue background indicates that the domain is not in the aligned region.

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