Protein Alignment NSUN2 and nsun2

DIOPT Version :10

• Sequence 1: NP_060225.4
• Gene: NSUN2 / 54888
• HGNCID: 25994
• Length: 767
• Species: Homo sapiens
• Sequence 2: NP_956005.1
• Gene: nsun2 / 325292
• ZFINID: ZDB-GENE-030131-4017
• Length: 706
• Species: Danio rerio
• Alignment Length: 707
• Identity: 499/707 - (70%)
• Similarity: 568/707 - (80%)
• Gaps: 19/707 - (2%)

Human    67 MDALREPLPATLRITGYKSHAKEILHCLKNKYFKELEDLEVDGQKVEVPQPLSWYPEELAWHTNL 131
            |:|:|||||||:||||||||||||||.||.|||||::||||||||:|.||||||||:||||||||
Zfish     1 MEAMREPLPATIRITGYKSHAKEILHTLKEKYFKEVQDLEVDGQKIEAPQPLSWYPDELAWHTNL 65

Human   132 SRKILRKSPHLEKFHQFLVSETESGNISRQEAVSMIPPLLLNVRPHHKILDMCAAPGSKTTQLIE 196
            |||||||||.|||||||||||||||||||||||||||||||.:.|.||||||||||||||.||||
Zfish    66 SRKILRKSPLLEKFHQFLVSETESGNISRQEAVSMIPPLLLKIEPQHKILDMCAAPGSKTAQLIE 130

Human   197 MLHADMNVPFPEGFVIANDVDNKRCYLLVHQAKRLSSPCIMVVNHDASSIPRLQIDVDGRKEILF 261
            |||:||:||||||||||||||||||||||||||||:|||||||||||||||||..|.:|:|:|||
Zfish   131 MLHSDMDVPFPEGFVIANDVDNKRCYLLVHQAKRLNSPCIMVVNHDASSIPRLHFDNNGKKDILF 195

Human   262 YDRILCDVPCSGDGTMRKNIDVWKKWTTLNSLQLHGLQLRIATRGAEQLAEGGRMVYSTCSLNPI 326
            ||||||||||||||||||||||||||||.|||.|||||||||.||.||||.||||||||||||||
Zfish   196 YDRILCDVPCSGDGTMRKNIDVWKKWTTSNSLHLHGLQLRIAVRGVEQLAVGGRMVYSTCSLNPI 260

Human   327 EDEAVIASLLEKSEGALELADVSNELPGLKWMPGITQWKVMTKDGQWFTDWDAVPHSRHTQIRPT 391
            |||||||:|||||||:|||||.|.:|||||:|||||.||||||:||||:::..||.|||||||||
Zfish   261 EDEAVIAALLEKSEGSLELADASPDLPGLKYMPGITSWKVMTKEGQWFSNFSEVPTSRHTQIRPT 325

Human   392 MFPPKDPEKLQAMHLERCLRILPHHQNTGGFFVAVLVKKSSMPWNKRQPKLQGKSAETRESTQLS 456
            ||||.|.|||..|.||||:||||||||||||||||||||:.||||:|.|||:.|  |...|.:::
Zfish   326 MFPPSDSEKLTEMRLERCVRILPHHQNTGGFFVAVLVKKAPMPWNRRHPKLRNK--EVSSSGEVA 388

Human   457 PAD-------LTEGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSKKDGVCGPPPSKKMKLFG 514
            |.:       .|:..|.|....::|...|..:..:....|.:|   .||:.||||||.|||||||
Zfish   389 PVEELQMDESPTDVPPADGPSTDAPVEEGERNPSVPETPEPVE---VKKENVCGPPPPKKMKLFG 450

Human   515 FKEDPFVFIPEDDPLFPPIEKFYALDPSFPRMNLLTRTTEGKKRQLYMVSKELRNVLLNNSEKMK 579
            ||||||||:.||||:||||:.||.|.|.||::|:||||.|||||.|||||||||||||||||:||
Zfish   451 FKEDPFVFLTEDDPIFPPIQSFYDLSPDFPKLNVLTRTHEGKKRHLYMVSKELRNVLLNNSERMK 515

Human   580 VINTGIKVWCRNNSGEEFDCAFRLAQEGIYTLYPFINSRIITVSMEDVKILLTQENPFFRKLSSE 644
            |||||:||..|||.||:|.|||||||||:|||.|:|.:|||.:|:||||:||||||||..||..|
Zfish   516 VINTGVKVLSRNNDGEQFGCAFRLAQEGVYTLCPYIRARIINISVEDVKVLLTQENPFLSKLGDE 580

Human   645 TYSQAKDLAKGSIVLKYEPDSANPDALQCPIVLCGWRGKASIRTFVPKNERLHYLRMMGLEVLGE 709
            .:.|||.|..|||||:|.||..:.||.||||.|||||||.|||.||.:|||||||||:|:||..:
Zfish   581 AHMQAKKLEMGSIVLRYLPDPKDLDAPQCPIDLCGWRGKTSIRAFVSRNERLHYLRMVGVEVFRD 645

Human   710 ---KKKEGVILTNESAASTGQ---PDNDVTEGQRAGEPNSPDAEEANSPD-VTAGCD 759
               |:.:|...|.|.:....:   .:.|:.|.:.|....|......|..: |::.||
Zfish   646 KQGKRNDGQTETQEESTEDAEGLSQEVDLVEQEGAETEKSSSESNPNGTELVSSTCD 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NSUN2	NP_060225.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36
		RsmB	<59..431	CDD:439914	313/363 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	436..481		14/51 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	719..767		9/45 (20%)
nsun2	NP_956005.1	RsmB	<1..365	CDD:439914	313/363 (86%)