Protein Alignment NSUN2 and Nsun2

DIOPT Version :10

• Sequence 1: NP_060225.4
• Gene: NSUN2 / 54888
• HGNCID: 25994
• Length: 767
• Species: Homo sapiens
• Sequence 2: NP_663329.3
• Gene: Nsun2 / 28114
• MGIID: 107252
• Length: 757
• Species: Mus musculus
• Alignment Length: 768
• Identity: 670/768 - (87%)
• Similarity: 695/768 - (90%)
• Gaps: 12/768 - (1%)

Human     1 MGRRSRGRRLQQQQRPEDAEDGAEGGGKRGEAGWEGGYPEIVKENKLFEHYYQELKIVPEGEWGQ 65
            ||||:||||.||..:||..||.::||.|||:||||||||||||||||||||||||||||||||.|
Mouse     1 MGRRARGRRFQQPPQPEGEEDASDGGRKRGQAGWEGGYPEIVKENKLFEHYYQELKIVPEGEWDQ 65

Human    66 FMDALREPLPATLRITGYKSHAKEILHCLKNKYFKELEDLEVDGQKVEVPQPLSWYPEELAWHTN 130
            ||::|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 FMESLREPLPATLRITGYKSHAKEILHCLKNKYFKELEDLEVDGQKVEVPQPLSWYPEELAWHTN 130

Human   131 LSRKILRKSPHLEKFHQFLVSETESGNISRQEAVSMIPPLLLNVRPHHKILDMCAAPGSKTTQLI 195
            ||||||||||.|.|||||||||||||||||||||||||||||||.||||||||||||||||||||
Mouse   131 LSRKILRKSPLLAKFHQFLVSETESGNISRQEAVSMIPPLLLNVEPHHKILDMCAAPGSKTTQLI 195

Human   196 EMLHADMNVPFPEGFVIANDVDNKRCYLLVHQAKRLSSPCIMVVNHDASSIPRLQIDVDGRKEIL 260
            |||||||:||||||||||||||||||||||||||||||||||||||||||||||.:|||||||||
Mouse   196 EMLHADMSVPFPEGFVIANDVDNKRCYLLVHQAKRLSSPCIMVVNHDASSIPRLTVDVDGRKEIL 260

Human   261 FYDRILCDVPCSGDGTMRKNIDVWKKWTTLNSLQLHGLQLRIATRGAEQLAEGGRMVYSTCSLNP 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 FYDRILCDVPCSGDGTMRKNIDVWKKWTTLNSLQLHGLQLRIATRGAEQLAEGGRMVYSTCSLNP 325

Human   326 IEDEAVIASLLEKSEGALELADVSNELPGLKWMPGITQWKVMTKDGQWFTDWDAVPHSRHTQIRP 390
            :|||||||:|||||||||||||||.||||||||||::||||||:|||||.||..||..|||||||
Mouse   326 VEDEAVIAALLEKSEGALELADVSAELPGLKWMPGVSQWKVMTRDGQWFADWHEVPQGRHTQIRP 390

Human   391 TMFPPKDPEKLQAMHLERCLRILPHHQNTGGFFVAVLVKKSSMPWNKRQPKLQGKSAETRESTQL 455
            |||||.|.||||||||||||||||||||||||||||||||:.|||||||||:|.||||.||....
Mouse   391 TMFPPTDLEKLQAMHLERCLRILPHHQNTGGFFVAVLVKKAPMPWNKRQPKVQNKSAEAREPRVS 455

Human   456 SPADLTEGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSKKDGVCGPPPSKKMKLFGFKEDPF 520
            |....|||.|:|.|:|||...||.||:|.||.||:.|:| .||||||||||||||||||||||||
Mouse   456 SHVAATEGNPSDQSELESQMITGAGDSETAHNTENTESN-EKKDGVCGPPPSKKMKLFGFKEDPF 519

Human   521 VFIPEDDPLFPPIEKFYALDPSFPRMNLLTRTTEGKKRQLYMVSKELRNVLLNNSEKMKVINTGI 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   520 VFIPEDDPLFPPIEKFYALDPSFPRMNLLTRTTEGKKRQLYMVSKELRNVLLNNSEKMKVINTGI 584

Human   586 KVWCRNNSGEEFDCAFRLAQEGIYTLYPFINSRIITVSMEDVKILLTQENPFFRKLSSETYSQAK 650
            |||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||.|||.|
Mouse   585 KVWCRNNSGEEFDCAFRLAQEGIYTLYPFINSRIITVSMEDVKTLLTQENPFFRKLSSEAYSQVK 649

Human   651 DLAKGSIVLKYEPDSANPDALQCPIVLCGWRGKASIRTFVPKNERLHYLRMMGLEVLGEKKKEGV 715
            ||||||:||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||
Mouse   650 DLAKGSVVLKYEPDSANPDTLQCPIVLCGWRGKASIRTFVPKNERLHYLRMMGLEVLGEKKKEGV 714

Human   716 ILTNESAASTGQP-DNDVTEGQRAGEPNSPDAEEANSPDVTAGCDPAGVHPPR 767
            |||||:|||..|| |.|..  |.|.:|..||:        ..|||.|...|.|
Mouse   715 ILTNENAASPEQPGDEDAK--QTAQDPCVPDS--------VPGCDAAAAEPSR 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NSUN2	NP_060225.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		22/34 (65%)
		RsmB	<59..431	CDD:439914	349/371 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	436..481		25/44 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	719..767		19/48 (40%)
Nsun2	NP_663329.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		21/33 (64%)
		RsmB	<59..431	CDD:439914	349/371 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	436..504		41/68 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	716..757		21/50 (42%)